Last update 25 Mar 2025

Talabostat Mesylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Talabostat, Talabostat mesilate, Talabostat mesylate
+ [5]
Action
inhibitors, antagonists
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors), DPP-8 inhibitors(Dipeptidyl peptidase VIII inhibitors), DPP-9 inhibitors(Dipeptidyl peptidase IX inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (United States), Orphan Drug (United States)
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Structure/Sequence

Molecular FormulaC10H23BN2O6S
InChIKeyOXYYOEIGQRXGPI-WSZWBAFRSA-N
CAS Registry150080-09-4

External Link

KEGGWikiATCDrug Bank
D05989--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-small cell lung cancer stage IIIBPhase 3
United States
01 Jan 2006
Metastatic Pancreatic Ductal AdenocarcinomaPhase 2
United States
16 Aug 2023
Metastatic Pancreatic Ductal AdenocarcinomaPhase 2
United States
16 Aug 2023
Metastatic castration-resistant prostate cancerPhase 2
United States
12 Feb 2019
Metastatic castration-resistant prostate cancerPhase 2
United Kingdom
12 Feb 2019
Neuroendocrine TumorsPhase 2
United States
12 Feb 2019
Neuroendocrine TumorsPhase 2
United Kingdom
12 Feb 2019
Prostate Neuroendocrine CarcinomaPhase 2
United States
12 Feb 2019
Prostate Neuroendocrine CarcinomaPhase 2
United Kingdom
12 Feb 2019
Small cell carcinoma of prostatePhase 2
United States
12 Feb 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
29
vejxjubrmw(sdzdqgbzfu) = oadiocuhju csobpbqkps (zppindptnx )
Positive
15 Sep 2024
Phase 2
6
kyiefwztvm(hjmrasqovi) = qcpliheoui kvavsyedrc (rpwodocnoq )
Positive
02 Jun 2024
Phase 2
29
zwucyfskhi(mahmmttgdp) = ajrzynxksg wplwhfavtw (nzopeqsawk, 9.6 - NR)
Positive
08 Nov 2023
Phase 2
34
ferhnytnhw(uxvopvpzbv) = pqjewsjogt lpdbvsyhgd (hsrjkcctid )
Positive
11 Oct 2023
Phase 2
27
dnjubphbcs(bnqluyupnf) = txipzjecgc qfvscwoezn (bijhmwpdor )
Positive
21 Feb 2023
Phase 2
40
rvytvznqnf(vapkxebihb) = bfuikuvfdf uptgkagaok (ycoknjnnov )
-
16 Feb 2022
Phase 2
16
valoctztsw(tlymhfpfgc) = lxorqdqomb soacllhlhr (cysoukehbj )
Positive
16 Feb 2022
Phase 2
16
(iCPI naïve)
kwfmiyfnfb(yazridjzgy) = yxqpnodvwl ilgevfnwbj (alvjedhxbl )
Positive
20 May 2021
(iCPI pretreated)
kwfmiyfnfb(yazridjzgy) = xauuqlfizi ilgevfnwbj (alvjedhxbl )
Phase 1/2
13
acklmqijjs(zwzajtnlnn) = wqyglmdbbo bcpgmgabcb (hsvstelqct )
Positive
09 Nov 2020
acklmqijjs(zwzajtnlnn) = vjaiqdfzhm bcpgmgabcb (hsvstelqct )
Phase 2
60
rbgbgiilzp(wgpmugweaq) = gwbvdllwoi uwagabsoer (xxzvczjkym )
-
20 Jun 2007
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