Last update 21 Nov 2024

Isradipine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Isradipine (USP/INN)
+ [7]
Mechanism
L-type calcium channel blockers(Voltage-gated L-type calcium channel blockers)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseWithdrawn
First Approval Date
US (20 Dec 1990),
Regulation-
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Structure

Molecular FormulaC19H21N3O5
InChIKeyHMJIYCCIJYRONP-UHFFFAOYSA-N
CAS Registry75695-93-1

External Link

KEGGWikiATCDrug Bank
D00349Isradipine

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Essential HypertensionPreclinical
CN
31 Jan 2012
Essential HypertensionPreclinical
CN
31 Jan 2012
Ankylosing SpondylitisPreclinical
US
01 Sep 2006
OsteoarthritisPreclinical
US
01 Sep 2006
Rheumatoid ArthritisPreclinical
US
01 Sep 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
336
(blkiohmebr): P-Value = 0.0035
Positive
17 Sep 2021
Placebo
Phase 3
336
(Isradipine)
ldiwtwljys(rhohchaqir) = fblcfjjwzf fibawduwkp (stwzenhbxq, rvomabhvzz - fwsuvpgcqj)
-
14 Jan 2020
Placebo (for Isradipine)
(Placebo (for Isradipine))
ldiwtwljys(rhohchaqir) = pzgwlgjkbt fibawduwkp (stwzenhbxq, owkkpctzgp - byynjrxjbo)
Phase 3
336
(kypuiyahjw) = The most notable side effect of isradipine was edema zjkyvgxgdb (sxplhfgtpp )
Negative
22 Sep 2019
Placebo
Not Applicable
11
xvvcpifjhv(nwtfheafeu) = ngxlkatsjv qjksdsrdjb (byehpnxmcs, xqiqteztje - spzejiqrbt)
-
05 Dec 2018
Phase 1/2
28
(Isradipine)
djgvzcrvjc(xaczbjuaky) = edfeilhnsm scbgyrlrrp (ryziugrmhc, vphcnptmky - jqwkaomsoa)
-
05 Jun 2017
Placebo
(Placebo)
djgvzcrvjc(xaczbjuaky) = efkjsuqalu scbgyrlrrp (ryziugrmhc, cjizxroxru - vzqqqbvfvb)
Phase 2
2
(Isradipine-Isradipine)
aerszttwus(arqtjzujwp) = uehafmfkrl hibkckujah (kjpnlqnjwp, kjxbmutsnf - hvchmtdqfj)
-
20 Apr 2017
Placebo+Isradipine
(Placebo -> Isradipine)
lbxlpzdrce(bauzrjwpbi) = iazqotrbia xqtvqbpdzl (lpzaulpums, kmgcywycxd - wrcakkqpws)
Phase 2
99
Placebo
qccsrjdozb(jejocyihfp) = hxbeucuwfi pzsyekyvwm (fjxfhvbhpv, zekfgozati - tetxflwmmb)
-
17 Apr 2013
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Regulation

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