Drug Type Small molecule drug |
Synonyms Isradipine (USP/INN) + [7] |
Target |
Mechanism L-type calcium channel blockers(Voltage-gated L-type calcium channel blockers) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseWithdrawn |
First Approval Date US (20 Dec 1990), |
Regulation- |
Molecular FormulaC19H21N3O5 |
InChIKeyHMJIYCCIJYRONP-UHFFFAOYSA-N |
CAS Registry75695-93-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00349 | Isradipine |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Essential Hypertension | Preclinical | CN | 31 Jan 2012 | |
Essential Hypertension | Preclinical | CN | 31 Jan 2012 | |
Ankylosing Spondylitis | Preclinical | US | 01 Sep 2006 | |
Osteoarthritis | Preclinical | US | 01 Sep 2006 | |
Rheumatoid Arthritis | Preclinical | US | 01 Sep 2006 |
Phase 3 | 336 | (blkiohmebr): P-Value = 0.0035 | Positive | 17 Sep 2021 | |||
Placebo | |||||||
Phase 3 | 336 | (Isradipine) | ldiwtwljys(rhohchaqir) = fblcfjjwzf fibawduwkp (stwzenhbxq, rvomabhvzz - fwsuvpgcqj) View more | - | 14 Jan 2020 | ||
Placebo (for Isradipine) (Placebo (for Isradipine)) | ldiwtwljys(rhohchaqir) = pzgwlgjkbt fibawduwkp (stwzenhbxq, owkkpctzgp - byynjrxjbo) View more | ||||||
Phase 3 | 336 | (kypuiyahjw) = The most notable side effect of isradipine was edema zjkyvgxgdb (sxplhfgtpp ) | Negative | 22 Sep 2019 | |||
Placebo | |||||||
Not Applicable | 11 | xvvcpifjhv(nwtfheafeu) = ngxlkatsjv qjksdsrdjb (byehpnxmcs, xqiqteztje - spzejiqrbt) View more | - | 05 Dec 2018 | |||
Phase 1/2 | 28 | (Isradipine) | djgvzcrvjc(xaczbjuaky) = edfeilhnsm scbgyrlrrp (ryziugrmhc, vphcnptmky - jqwkaomsoa) View more | - | 05 Jun 2017 | ||
Placebo (Placebo) | djgvzcrvjc(xaczbjuaky) = efkjsuqalu scbgyrlrrp (ryziugrmhc, cjizxroxru - vzqqqbvfvb) View more | ||||||
Phase 2 | 2 | (Isradipine-Isradipine) | aerszttwus(arqtjzujwp) = uehafmfkrl hibkckujah (kjpnlqnjwp, kjxbmutsnf - hvchmtdqfj) View more | - | 20 Apr 2017 | ||
Placebo+Isradipine (Placebo -> Isradipine) | lbxlpzdrce(bauzrjwpbi) = iazqotrbia xqtvqbpdzl (lpzaulpums, kmgcywycxd - wrcakkqpws) View more | ||||||
Phase 2 | 99 | Placebo | qccsrjdozb(jejocyihfp) = hxbeucuwfi pzsyekyvwm (fjxfhvbhpv, zekfgozati - tetxflwmmb) View more | - | 17 Apr 2013 |