Last update 21 Nov 2024

SX-682

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mechanism
CXCR1 antagonists(C-X-C motif chemokine receptor 1 antagonists), CXCR2 antagonists(C-X-C motif chemokine receptor 2 antagonists)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC19H14BF4N3O4S
InChIKeySDUDZBCEHIZMFZ-UHFFFAOYSA-N
CAS Registry1648843-04-2

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic CancerPhase 2
US
08 Nov 2023
Pancreatic CancerPhase 2
US
08 Nov 2023
metastatic non-small cell lung cancerPhase 2
US
06 Apr 2023
Recurrent Non-Small Cell Lung CancerPhase 2
US
06 Apr 2023
Metastatic colon cancerPhase 2
US
14 Oct 2020
Metastatic Colorectal CarcinomaPhase 2
US
14 Oct 2020
Metastatic Microsatellite Stable Colorectal CarcinomaPhase 2
US
14 Oct 2020
RAS mutant Colorectal CancerPhase 2
US
14 Oct 2020
Rectal AdenocarcinomaPhase 2
US
14 Oct 2020
Unresectable Colorectal CarcinomaPhase 2
US
14 Oct 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
51
PEM + SX-682(200 mg) expanded BID ≤100 mg
(fchutffzkf) = NO identified qcaqncatek (gdvvlbkhxk )
Positive
24 May 2024
PEM + SX-682(200 mg) expanded BID 150 mg
Phase 1
17
(vutkquyrlm) = slxdbmsbih tlljbuopjh (cspduuzhiz )
Positive
15 Nov 2022
(25 mg)
(lrirbrqqku) = ozusoycyqs xqjkvrmjqq (cvmopdwxoo )
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Clinical Trial

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Approval

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Regulation

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