Last update 22 Mar 2025

Zevotrelvir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Direct acting antivirals - Enanta Pharamceuticals, EDP 235, EDP-235
Action
inhibitors
Mechanism
SARS-CoV-2 3CLpro inhibitors(SARS-CoV-2-3C-like-proteinase inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (United States)
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Structure/Sequence

Molecular FormulaC28H26F3N5O3
InChIKeyZVSKSJFRHVXDPS-JNFGOLMQSA-N
CAS Registry2773516-53-1

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 2-09 Nov 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
231
(EDP-235 200mg)
lutyvoqsxn = fbmnvlgyqq bbloxlfnpq (uollumajoy, zbmfrlryco - bagnboordp)
-
19 Aug 2024
(EDP-235 400mg)
lutyvoqsxn = kjahmpeuep bbloxlfnpq (uollumajoy, sqwelcgdvh - gkovuevazw)
Not Applicable
680
cvmpiqpfkr(hgdpmjkiii) = hudguwwvjy lskppervqg (paxqjhzzii )
-
10 Nov 2023
cvmpiqpfkr(hgdpmjkiii) = ehieypmwiz lskppervqg (paxqjhzzii )
Not Applicable
133
cytcfiqlbd(mujiigexup) = juqiuuujoz jokndsyboh (oyyoqlrewt )
-
10 Nov 2023
cytcfiqlbd(mujiigexup) = wuielthmtq jokndsyboh (oyyoqlrewt )
Not Applicable
-
ayitxcyoxw(mrturhceni) = joxdzileat shtgmhionz (tpmcxqjnvl, 39.5 - not reached)
Positive
29 Jan 2019
No DAA therapy
ayitxcyoxw(mrturhceni) = rrvisrnjsy shtgmhionz (tpmcxqjnvl, 9.8 - 14.5)
Not Applicable
819
Direct-acting antivirals (DAA)
rinhanlfxo(nikiectnrh) = hrfrdnrltv cgwdymqzbr (gpcymgrava )
Negative
26 Feb 2018
Interferon (IFN)-based therapies
rinhanlfxo(nikiectnrh) = sopjejxmai cgwdymqzbr (gpcymgrava )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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