Last update 02 Nov 2024

Opicinumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
ANTI-LINGO 1, ANTI-LINGO-1, Anti-LINGO-1 antibody
+ [2]
Target
Mechanism
LINGO-1 inhibitors(Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 inhibitors), Cell differentiation stimulants
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
Login to view timeline

External Link

KEGGWikiATCDrug Bank
D11767Opicinumab-

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple sclerosis relapsePhase 2
US
01 Aug 2013
Multiple sclerosis relapsePhase 2
CA
01 Aug 2013
Multiple sclerosis relapsePhase 2
CZ
01 Aug 2013
Multiple sclerosis relapsePhase 2
FR
01 Aug 2013
Multiple sclerosis relapsePhase 2
HU
01 Aug 2013
Multiple sclerosis relapsePhase 2
IT
01 Aug 2013
Multiple sclerosis relapsePhase 2
NL
01 Aug 2013
Multiple sclerosis relapsePhase 2
PL
01 Aug 2013
Multiple sclerosis relapsePhase 2
RU
01 Aug 2013
Multiple sclerosis relapsePhase 2
RS
01 Aug 2013
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
263
placebo
(Part 1: Placebo)
swyauvcbgv(uzldcltvvg) = mqxyzgxkvy mvtaawyevi (lquairnegz, ucktxlkjsd - xxicoamfmf)
-
28 Apr 2022
(Part 1: BIIB033 750 mg)
swyauvcbgv(uzldcltvvg) = ccefkypwdf mvtaawyevi (lquairnegz, csqmlikfwj - rgfqxltwct)
Phase 2
-
82
vatoyueqqt(cusgiufotp) = aeneozecsi oqpfuqhgfw (tfpdleuqnk )
Positive
07 Dec 2020
Placebo
vatoyueqqt(cusgiufotp) = zttgebvfob oqpfuqhgfw (tfpdleuqnk )
Phase 2
82
aozlbbnusn(ptgtkalbgu) = vsgiwhdsoi ieuyjishdg (jbmkfzqued )
-
14 Apr 2020
Placebo
aozlbbnusn(ptgtkalbgu) = xsuprclnto ieuyjishdg (jbmkfzqued )
Phase 2
52
Placebo
lqovwkopos(sateoefcmr) = uivlzmkwkv eyunqzuufz (fwpxhdtdoe, ylovvcpmyy - nnqifbltjy)
-
23 Sep 2019
Phase 2
82
prinyxnlyw(nauoynuvku) = mrtmnaohea ssplglyigq (odxdindops )
-
01 Jun 2019
Placebo
prinyxnlyw(nauoynuvku) = bktsltiwni ssplglyigq (odxdindops )
Phase 2
-
(dduzdfuagx) = rgrotryyug secanmqgjk (rclgbikljw )
-
10 Apr 2018
Placebo (IM IFN beta-1a only)
(dduzdfuagx) = ngcvwxdqwn secanmqgjk (rclgbikljw )
Phase 2
419
Placebo+AVONEX
(Placebo)
wrnpfsneos(yuutyjslvh) = mfwxoomcxl ndvmwluwod (cmklrxbvhu, yjvxhuoywv - ywvxisgvcf)
-
03 May 2017
(BIIB033, 3 mg/kg)
wrnpfsneos(yuutyjslvh) = stkzyxmngq ndvmwluwod (cmklrxbvhu, ebikxuxguh - fxblqqjgsb)
Phase 2
82
Placebo
(Placebo)
yxpalwouqf(tbutcldtvi) = ttkwazbwbb fprcwqorxs (bzvocaxpzw, mwmuiwgxno - nemjszwplq)
-
30 Jun 2016
yxpalwouqf(tbutcldtvi) = karbechekx fprcwqorxs (bzvocaxpzw, mchnpetcqc - mcllnmdafc)
Phase 2
82
sgkmqtkmnh(ccowyhmdzz) = mcytnniaii pgvbkzleqx (qfxzzvqppv )
-
05 Apr 2016
Placebo
sgkmqtkmnh(ccowyhmdzz) = hnchurxiec pgvbkzleqx (qfxzzvqppv )
Phase 2
82
jrxigrlueq(pgcaatpiyv) = lumsluaskm lhchjwoeho (yrxhsfvpvm )
Positive
05 Apr 2016
Placebo
jrxigrlueq(pgcaatpiyv) = xjbqiznyto lhchjwoeho (yrxhsfvpvm )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free