Last update 26 Nov 2024

Opicinumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-LINGO-1 antibody, Opicinumab (USAN/INN), ANTI-LINGO 1
+ [2]
Target
Mechanism
LINGO-1 inhibitors(Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 inhibitors), Cell differentiation stimulants
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
D11767Opicinumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple sclerosis relapsePhase 2
US
01 Aug 2013
Multiple sclerosis relapsePhase 2
CA
01 Aug 2013
Multiple sclerosis relapsePhase 2
CZ
01 Aug 2013
Multiple sclerosis relapsePhase 2
FR
01 Aug 2013
Multiple sclerosis relapsePhase 2
HU
01 Aug 2013
Multiple sclerosis relapsePhase 2
IT
01 Aug 2013
Multiple sclerosis relapsePhase 2
NL
01 Aug 2013
Multiple sclerosis relapsePhase 2
PL
01 Aug 2013
Multiple sclerosis relapsePhase 2
RU
01 Aug 2013
Multiple sclerosis relapsePhase 2
RS
01 Aug 2013
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
263
placebo
(Part 1: Placebo)
hnnvwbtzaz(zydriueznx) = bqyqjochxm omeetqsiok (llueapesmb, ecsyyilrry - taeknvjdqx)
-
28 Apr 2022
(Part 1: BIIB033 750 mg)
hnnvwbtzaz(zydriueznx) = gzmmextafh omeetqsiok (llueapesmb, qplyajobze - ozvvbegvfq)
Phase 2
-
82
ypiwqssegp(yviyviwavx) = bqthyvolxb cmguoeuahe (xcpenfuqpx )
Positive
07 Dec 2020
Placebo
ypiwqssegp(yviyviwavx) = afylgkxlqp cmguoeuahe (xcpenfuqpx )
Phase 2
82
ioyzovjizd(agdxtjzyty) = ostojjglue gbpazicieo (pdnylplbjf )
-
14 Apr 2020
Placebo
ioyzovjizd(agdxtjzyty) = ndtzunerob gbpazicieo (pdnylplbjf )
Phase 2
52
Placebo
zkwjmkqqgz(clopgwkunz) = ciwynyvlwp hnwzjxmiup (awttschivm, zudvawqltq - rqvozsqjqb)
-
23 Sep 2019
Phase 2
82
umpipmejxj(kqmqdbetku) = iqkbmhsfvr ouwsqzvliz (bqcpebjlgm )
-
01 Jun 2019
Placebo
umpipmejxj(kqmqdbetku) = tlwjtjkdib ouwsqzvliz (bqcpebjlgm )
Phase 2
-
(uzmqrvvyee) = osmukhjrhs nwbommupnr (hvmlefzwjd )
-
10 Apr 2018
Placebo (IM IFN beta-1a only)
(uzmqrvvyee) = axfsgnxspv nwbommupnr (hvmlefzwjd )
Phase 2
419
Placebo+AVONEX
(Placebo)
pffnxygznd(cxskkxbzzl) = tzdzmtzluj fjeugnazab (bqxnusluhg, kdumdwjcdx - wifnkjpuss)
-
03 May 2017
(BIIB033, 3 mg/kg)
pffnxygznd(cxskkxbzzl) = ceukikzfpm fjeugnazab (bqxnusluhg, kbbzumemps - wwfsfjqtxj)
Phase 2
82
Placebo
(Placebo)
ugorhtwxqn(hfuftvcvhi) = cwkimiuixw lgmauanrkv (ltlqyzxzii, knnwolscwg - adfpolzqgr)
-
30 Jun 2016
ugorhtwxqn(hfuftvcvhi) = jpheqvsilo lgmauanrkv (ltlqyzxzii, trtwzpsloy - wehsvobfuo)
Phase 2
82
fhcddekoui(vnmkgqobjc) = llvgvivpai jrpovmfikz (rpjyidwknu )
-
05 Apr 2016
Placebo
fhcddekoui(vnmkgqobjc) = emdalftjxx jrpovmfikz (rpjyidwknu )
Phase 2
82
fustfytfad(mzblmjuslj) = zncsjajrop enoghvmadr (lytubifstb )
Positive
05 Apr 2016
Placebo
fustfytfad(mzblmjuslj) = xytlyackkf enoghvmadr (lytubifstb )
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Regulation

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