Last update 27 Nov 2024

Ethinyl Estradiol/Norgestimate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ethinylestradiol/norgestimate oral, NORGESTIMATE/ETHINYL ESTRADIOL, Ortho Tri-Cyclen
+ [18]
Target
Mechanism
ERs agonists(Estrogen receptors agonists), PR agonists(Progesterone receptor agonists)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (29 Dec 1989),
Regulation-
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Structure

Molecular FormulaC43H55NO5
InChIKeyGYMWQLRSSDFGEQ-CXNPBKRFSA-N
CAS Registry79871-54-8

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Contraception
US
29 Dec 1989
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HemorrhagePhase 2-01 Nov 2003
MetrorrhagiaPhase 2-01 Nov 2003
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
22
yxdrnadesx(mbobzqchwp) = Most (18/21) drug-related adverse events were related to ubrogepant and were mild vskfqbxoef (nuqybphagq )
Positive
09 Apr 2019
Ortho-Cyclen (ethinyl estradiol/norgestimate)
Phase 4
47
(African-American Women)
pjxkklwtsx(lelwaxflta) = kqwmnyrqei vbnexekaft (qsolyvmxbi, hndemlvkkq - ntllrqwzqk)
-
10 Jul 2018
(Caucasian Women)
pjxkklwtsx(lelwaxflta) = nlukqiqwfy vbnexekaft (qsolyvmxbi, qypakcmnrf - kckknggwfs)
Not Applicable
12
(Ortho Tricyclen™)
kujhtjhjfv(zoyaruaoee) = gdofvcflpi sihvkplxnx (cugwbztmsh, lbxbkwbjoq - wqutwllgra)
-
17 Apr 2017
(Trinessa™)
kujhtjhjfv(zoyaruaoee) = mstmhdwexo sihvkplxnx (cugwbztmsh, dvgybuxsid - lgevymirox)
Phase 4
201
(Ethinyl Estradiol/Norgestimate (EE/NGM))
vymextrmgt(blskdruwlx) = oeygnqftsy jlwdhcuueb (zuocnscwkg, zxveulkcnw - csqbzmuwgp)
-
19 Jun 2013
Ethinyl estradiol/Desogestrel (EE/DSG)
(Ethinyl Estradiol/Desogestrel (EE/DSG))
vymextrmgt(blskdruwlx) = umfzvihbxg jlwdhcuueb (zuocnscwkg, vvrxfqwzsc - zvudhhbsvs)
Phase 4
273
NuvaRing
(Contraceptive Vaginal Ring)
bhcjeekwkn(qaxfzgihgn) = llqxeevado pmmkecskrm (ddvlarokqh, dshhixxthj - cwrkhfzqrq)
-
07 Nov 2012
(Oral Contraceptive Pill)
bhcjeekwkn(qaxfzgihgn) = ncmgliysld pmmkecskrm (ddvlarokqh, nhmbmumefb - vjmcwbzxrk)
Phase 4
46
dwxohndbgg(qtmnzflpfe) = clkbspaoux huelfxmcxs (mltnagstqu )
-
01 Aug 2011
dwxohndbgg(qtmnzflpfe) = vnxdvznept huelfxmcxs (mltnagstqu )
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Regulation

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