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Clinical Trials associated with PEGylated thrombopoietin(Chongqing Paijin Biotechnology Co Ltd)A Phase 1b, Open-label, Single-arm, Dose-escalation Study of PN20 in Patients with Primary Immune Thrombocytopenia (ITP)
The main aim of this clinical trial is to assess the safety and tolerability of PN20 in adult patients with primary immune thrombocytopenia (ITP). The main questions it aims to answer are:
* Is PN20 safe in these patients?
* Could these patients potentially benefit from PN20 treatment?
Participants will
* Receive one subcutaneous injection of PN20 according to weight;
* Visit the clinic for assessment.
评价注射用聚乙二醇化促血小板生成肽(PN20)单次给药在成人原发免疫性血小板减少症患者的研究
[Translation] A study evaluating the efficacy of a single dose of pegylated thrombopoietic peptide for injection (PN20) in adult patients with primary immune thrombocytopenia
主要目的:评价PN20在成人原发免疫性血小板减少症患者中的安全性和耐受性并探索合适的给药剂量和治疗周期。
次要目的:①评价PN20在成人ITP患者中的药代动力学、药效动力学及免疫原性特征;② 评价PN20在成人ITP患者中的初步疗效。
[Translation] Primary objective: To evaluate the safety and tolerability of PN20 in adult patients with primary immune thrombocytopenia and explore the appropriate dosage and treatment cycle.
Secondary objectives: ① To evaluate the pharmacokinetics, pharmacodynamics and immunogenicity characteristics of PN20 in adult patients with ITP; ② To evaluate the preliminary efficacy of PN20 in adult patients with ITP.
A Single-arm, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetic, Pharmacodynamics and Immunogenicity of PN20 for the Prevention of Chemotherapy-induced Thrombocytopenia in Patients With Lymphoma or Solid Tumor
The main aim of this clinical trial is to assess the safety and tolerability of PN20 in adult patients with chemotherapy-induced thrombocytopenia (CID). The main questions it aims to answer are:
* Is PN20 safe in these patients?
* Could these patients potentially benefit from PN20 prevention? Participants will
* Receive subcutaneous injections of PN20 according to weight on the first day of chemotherapy cycle, within 1 hour before the administration of chemotherapy drugs,
* Visit the clinic on Day 1 (D1), D2, D3, D4, D5, D8, D11, D13, D15 and D21 for assessment.
100 Clinical Results associated with PEGylated thrombopoietin(Chongqing Paijin Biotechnology Co Ltd)
100 Translational Medicine associated with PEGylated thrombopoietin(Chongqing Paijin Biotechnology Co Ltd)
100 Patents (Medical) associated with PEGylated thrombopoietin(Chongqing Paijin Biotechnology Co Ltd)
100 Deals associated with PEGylated thrombopoietin(Chongqing Paijin Biotechnology Co Ltd)