Last update 20 Mar 2025

ENG-002

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
GABRA2 x GABRA3 x GABRA5 x α1A-AR
Action
modulators, agonists
Mechanism
GABRA2 modulators(Gamma-aminobutyric acid A receptor alpha-2 modulators), GABRA3 modulators(Gamma-aminobutyric acid A receptor alpha-3 modulators), GABRA5 modulators(Gamma-aminobutyric acid A receptor alpha-5 modulators)
+ [1]
Therapeutic Areas
Nervous System DiseasesSkin and Musculoskeletal Diseases
Active Indication-
Inactive Indication
Muscle SpasticityPain
Originator Organization
Engrail Therapeutics, Inc.Engrail Therapeutics, Inc.Startup
Active Organization-
Inactive Organization
Engrail Therapeutics, Inc.Engrail Therapeutics, Inc.Startup
Drug Highest PhaseDiscontinuedPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with ENG-002
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100 Translational Medicine associated with ENG-002
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100 Patents (Medical) associated with ENG-002
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100 Deals associated with ENG-002
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Muscle SpasticityPreclinical
United States
Engrail Therapeutics, Inc.Engrail Therapeutics, Inc.Startup
15 Mar 2023
PainPreclinical
United States
Engrail Therapeutics, Inc.Engrail Therapeutics, Inc.Startup
15 Mar 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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