Last update 14 Jun 2025

TD-1058

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
ALK5
Action
inhibitors
Mechanism
ALK5 inhibitors(Transforming growth factor beta receptor 1 inhibitors)
Therapeutic Areas
Respiratory DiseasesOther Diseases
Active Indication-
Inactive Indication
Idiopathic Pulmonary Fibrosis
Originator Organization
Theravance Biopharma, Inc.Theravance Biopharma, Inc.
Active Organization-
Inactive Organization
Theravance Biopharma, Inc.Theravance Biopharma, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with TD-1058
NCT04589260
/ TerminatedPhase 1
A Ph 1, Rndmzd, Dbl-Blinded, Pbo-Controlled, 4-Part Study to Eval the Safety, Tolerability, PK, and PD of TD-1058 Admin by Inhalation of Single (A) and Multiple (B) Ascending Doses in Healthy Subjs and Subjs With IPF (C) and Following Admin Microtracer Doses (D)
100 Clinical Results associated with TD-1058
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100 Translational Medicine associated with TD-1058
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100 Patents (Medical) associated with TD-1058
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100 Deals associated with TD-1058
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Idiopathic Pulmonary FibrosisPhase 1
United Kingdom
Theravance Biopharma, Inc.Theravance Biopharma, Inc.
15 Oct 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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