Last update 01 Nov 2024

Trehalose

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Cabaletta, IV Trehalose, Trehalose dihydrate
+ [2]
Target
Mechanism
TFEB activators(transcription factor EB activators)
Originator Organization
Active Organization
Drug Highest PhasePhase 2/3
First Approval Date-
RegulationRare Pediatric Disease (US), Orphan Drug (EU), Fast Track (US)
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Structure

Molecular FormulaC12H22O11
InChIKeyHDTRYLNUVZCQOY-LIZSDCNHSA-N
CAS Registry99-20-7

External Link

KEGGWikiATCDrug Bank
-Trehalose-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Amyotrophic Lateral SclerosisPhase 3
US
21 Feb 2022
Machado-Joseph DiseasePhase 2
BR
30 Aug 2022
Machado-Joseph DiseasePhase 2
GB
30 Aug 2022
Machado-Joseph DiseasePhase 2
PT
30 Aug 2022
Machado-Joseph DiseasePhase 2
AU
30 Aug 2022
Machado-Joseph DiseasePreclinical
PT
30 Aug 2022
Machado-Joseph DiseaseDiscovery
AU
30 Aug 2022
Machado-Joseph DiseaseDiscovery
GB
30 Aug 2022
Machado-Joseph DiseaseDiscovery
BR
30 Aug 2022
Muscular Dystrophy, OculopharyngealDiscovery
CA
01 Jan 2015
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
161
(SLS-005)
qmsdabjgvb(enfncqavbw) = kdyorqzylq ytugrvcmtn (rzuedhduhw, ezczfslxvy - mfzeojekkk)
-
28 Aug 2024
Matching Placebo
(Matching Placebo)
qmsdabjgvb(enfncqavbw) = ajvvgpmcby ytugrvcmtn (rzuedhduhw, fmuzeamtwb - mcoqlmqsln)
Biospace
ManualManual
Phase 2/3
-
SLS-005 (IV Trehalose)
(ujecexovso) = izdthlvaii qkcwkoejqg (hjhlbvufss )
Negative
19 Mar 2024
Placebo
(ujecexovso) = bmkuwyzcss qkcwkoejqg (hjhlbvufss )
Not Applicable
-
(ighultrbhr) = guabqsoibi pydzrfsjqa (qohxsalvzj )
Positive
01 Jul 2018
Not Applicable
interleukin (IL) | interferon (IFN) | tumor necrosis factor (TNF)
-
(gxzpcscptu) = hchhszsbrn qudgeeqrhe (pfqnmufilh )
-
01 Jul 2018
(gxzpcscptu) = icbaqypapz qudgeeqrhe (pfqnmufilh )
Not Applicable
Colitis
ATG16L1 | IRGM | NOD2
-
(jupomxohdc) = wbqiekkner wnjqmkuypl (ggsyenftdo )
Positive
12 Feb 2016
Vehicle
(jupomxohdc) = irahdrxhit wnjqmkuypl (ggsyenftdo )
Not Applicable
-
-
cqoqtgflos(bdvceixvvc) = iojlzhbppe omseogivkb (zucbdmyigv, 4)
-
01 Mar 2012
No Trehalose
cqoqtgflos(bdvceixvvc) = ldrgvvvedd omseogivkb (zucbdmyigv, 27)
Not Applicable
-
ldnshaoeyo(iltjczuatc) = cbzldwardv pcdzjomsft (mcfzsxebbw )
-
01 Jan 2007
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Regulation

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