Last update 09 Jul 2025

PEPIDH1M vaccine(Duke University)

Overview

Basic Info

Drug Type
Synthetic peptide vaccine, Therapeutic vaccine
Synonyms
PEPIDH1M
Target
IDH1 R132H
Action
inhibitors
Mechanism
IDH1 R132H inhibitors, Epigenetic drug
Therapeutic Areas
NeoplasmsNervous System Diseases
Active Indication
IDH1-mutant Glioma
Inactive Indication-
Originator Organization
Duke UniversityDuke University
Active Organization
Duke UniversityDuke University
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with PEPIDH1M vaccine(Duke University)
NCT05609994
/ RecruitingPhase 1IIT
ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas
NCT02193347
/ CompletedPhase 1IIT
Patients With IDH1 Positive Recurrent Grade II Glioma Enrolled in a Safety and Immunogenicity Study of Tumor-Specific Peptide Vaccine
100 Clinical Results associated with PEPIDH1M vaccine(Duke University)
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100 Translational Medicine associated with PEPIDH1M vaccine(Duke University)
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100 Patents (Medical) associated with PEPIDH1M vaccine(Duke University)
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100 Deals associated with PEPIDH1M vaccine(Duke University)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
IDH1-mutant GliomaPhase 1
United States
Duke UniversityDuke University
28 Jan 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT02193347 (RESIST, CTgov)
Phase 1
IDH1-mutant Glioma
24
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-
15 Mar 2021
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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