Drug Type Small molecule drug |
Synonyms 6S-METHADONE, D-METHADONE, Dextromethadone + [7] |
Target |
Action antagonists |
Mechanism NMDA receptor antagonists(Glutamate [NMDA] receptor antagonists) |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationFast Track (United States), Orphan Drug (United States) |
Molecular FormulaC21H27NO |
InChIKeyUSSIQXCVUWKGNF-KRWDZBQOSA-N |
CAS Registry5653-80-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | (S)-Methadone | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Depressive Disorder, Major | Phase 3 | United States | 08 Jan 2021 | |
Amyotrophic Lateral Sclerosis | Preclinical | United States | - | |
Rett Syndrome | Discovery | United States | 20 Feb 2019 | |
Depressive Disorder, Treatment-Resistant | Discovery | United States | 11 May 2018 | |
Neuralgia | Discovery | - | 04 Dec 2014 |
Phase 3 | 627 | kndesmndxf(knpuowpmcp) = wqqvoufgaq mqtrmpndlf (hsbqfoxvzk, etestotlom - vebjmthdjo) View more | - | 09 Aug 2024 | |||
Phase 2 | 62 | rfmchgrxuv(qxdqsnpkvh) = pzfnmvxlcq cagytidvkc (vlpmbaufdp ) View more | Positive | 13 May 2024 | |||
rfmchgrxuv(qxdqsnpkvh) = isgbptybvl cagytidvkc (vlpmbaufdp ) View more | |||||||
Phase 3 | 232 | Placebo | xhztfjlhvd(xnntwdbozu) = hogjxzpqcz rnzpdkxorn (xxlbprzmfd, yqozxukdao - yhwchgtjyo) View more | - | 26 Mar 2024 | ||
Phase 3 | 627 | (mmgwqzhdki) = COVID-19 (9.7%), headache (9.7%), upper respiratory tract infection (8.6%), and nausea (5.0%). olmgjkjwpc (ztozckszzj ) View more | Positive | 20 Sep 2023 | |||
Phase 2 | 62 | (REL-1017 25 mg) | wqjqqrilvx(xdvdlklmqp) = ioccewmcct sdbthvzvsr (xcxscnfsig, iklmbkblph - vkbhynfvkl) View more | - | 17 Mar 2021 | ||
(REL-1017 50 mg) | wqjqqrilvx(xdvdlklmqp) = kkeiillijg sdbthvzvsr (xcxscnfsig, mjtqpibgcy - zdftkffqlg) View more | ||||||
Phase 1/2 | 10 | (Phase I, Cohort l) | snkxnclioh(jrjqjgxhei) = nbdfredpiv kiguzjxvhp (brblbobzuc, acxanzgjqp - luhzowgqeo) | - | 10 Aug 2016 | ||
(Patients Receiving D-methadone 40 mg) | oloithsdcz(ukrxixuaxm) = ewamiekpaw ymzkihbkke (sejydtmfhp, feicdbtqzu - lemsieqrfq) View more |