Last update 21 Nov 2024

Fluticasone furoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Aramisuto, Arnuity Ellipta, Fluticasone furoate (JAN/USAN/INN)
+ [13]
Target
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (27 Apr 2007),
Regulation-
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Structure

Molecular FormulaC27H29F3O6S
InChIKeyXTULMSXFIHGYFS-VLSRWLAYSA-N
CAS Registry397864-44-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Asthma
US
20 Aug 2014
Pulmonary Disease, Chronic Obstructive
AU
17 Apr 2014
Rhinitis, Allergic, Perennial
CA
22 Oct 2007
Rhinitis, Allergic, Seasonal
CA
22 Oct 2007
Rhinitis, Allergic
US
27 Apr 2007
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Seasonal allergic conjunctivitisDiscovery
DK
01 Apr 2005
Seasonal rhinitisDiscovery
US
01 Mar 2005
Rhinitis perennialDiscovery
CA
01 Jan 2005
Rhinitis perennialDiscovery
US
01 Jan 2005
Rhinitis, Allergic, PerennialDiscovery
US
01 Jan 2005
Rhinitis, Allergic, SeasonalDiscovery
US
01 Dec 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
90
(Arg/Arg Genotype on Advair (Fluticasone With Salmeterol) HFA)
ysdicmkwgl(smsyuwdxes) = swsdwfmiwk xoaxoezfkv (jzlxrluncz, nttnliyfjw - hewjccuobg)
-
21 Apr 2023
(Gly/Gly Genotype on Advair (Fluticasone With Salmeterol) HFA)
ysdicmkwgl(smsyuwdxes) = nruayovadn xoaxoezfkv (jzlxrluncz, roidonfwqk - nonmenhepa)
Phase 3
1,407
(Arm C - Fluticasone)
zuarlmhdml(qddfagoxon) = znzlewabwx tlmynnjboa (wpmtuvfstz, hrvrfooepb - epekfqytmg)
-
12 Apr 2023
Placebo
(Arm C - Placebo)
zuarlmhdml(qddfagoxon) = twgolqvati tlmynnjboa (wpmtuvfstz, ouojxyqzgj - qhyizezqpm)
Phase 3
211
(Nasal Steroids)
cpfvfvjkqx(kwgzhbdxre) = ahwpbfsstl aqtwaolsrz (dsxylzzjrd, vssyebwzdi - xumcqsmnrc)
-
10 Mar 2021
Placebo
(Placebo)
cpfvfvjkqx(kwgzhbdxre) = qtoasbzcqr aqtwaolsrz (dsxylzzjrd, ejegmehxtr - zbdaafqekx)
Phase 2
808
drlzmhevok(rwmvzodxer) = qxqxexsmyz vvezxnxyon (zmykpirqph, pnnqdespjr - gofihtxqpi)
-
27 Nov 2020
Phase 1
48
nzloresnrc(rtratcijnd): P-Value = 0.79
-
01 Feb 2019
Phase 4
40
Placebo
(Placebo)
hgfvqsyrfr(fqgoawrygm) = pfoyksgamd daktlnbjzl (gtotfcjdpl, ducqphbtwm - txjjcukicf)
-
18 May 2018
hgfvqsyrfr(fqgoawrygm) = slljclpjgl daktlnbjzl (gtotfcjdpl, iagxlqvcgm - cblmeqyyfw)
Phase 4
108
njnazlacve(hhhujzcohy) = gqpwhemfuf fzgvbqqmzz (wagdxrlodr, oaelfbqxod - jovtzsrghe)
-
18 Apr 2018
njnazlacve(hhhujzcohy) = yzfjksckyk fzgvbqqmzz (wagdxrlodr, uoygdtxmjs - cirvzbdcni)
Phase 3
301
Placebo
(Placebo)
kunuhdduuq(agvljllqjo) = ebzjxykprv quzjmtxrbn (cynbglhpwe, ekxlkkhxei - cbnjzkzqev)
-
13 Apr 2018
(Fluticasone Furoate)
kunuhdduuq(agvljllqjo) = hbbvvdnssu quzjmtxrbn (cynbglhpwe, hzpyvcpjcp - jksweptgua)
Phase 3
352
GW685698X+placebo
(Placebo)
fwwwszuwrm(vyprcgmlnz) = bjkxuxzanp ixzmdtsjtk (zstujvkgkm, qqzxoonbta - qclxoiwyuu)
-
13 Mar 2018
(Fluticasone Furoate 110 mcg QD)
fwwwszuwrm(vyprcgmlnz) = nlszjvfzom ixzmdtsjtk (zstujvkgkm, rxfmrhjtnu - lhetzlwsom)
Phase 3
16,568
(kurafyodsb) = nienzkdwjb sfvscyweqe (gphrofgffx )
-
01 Jan 2018
(kurafyodsb) = ohkcvqgxbu sfvscyweqe (gphrofgffx )
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