Last update 19 Jun 2024

Ningetinib Tosylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ct-053 free base, Ct-053-ptsa free base, Ct053ptsa free base
+ [4]
Mechanism
AXL inhibitors(AXL receptor tyrosine kinase inhibitors), FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors), MerTK inhibitors(Tyrosine-protein kinase Mer inhibitors)
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

Structure

Molecular FormulaC38H37FN4O8S
InChIKeyNAUYISNCVNUUDK-UHFFFAOYSA-N
CAS Registry1394820-77-9

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatocellular CarcinomaPhase 2-01 Dec 2020
Metastatic Renal Cell CarcinomaPhase 2
CN
25 Jun 2018
Renal Cell CarcinomaPhase 2
CN
25 Jun 2018
Non-Small Cell Lung CancerPhase 2
CN
01 Nov 2016
Kidney NeoplasmsPhase 1
CN
30 Jan 2022
LeukemiaPhase 1
CN
30 Jan 2022
FLT3 positive Acute Myeloid LeukemiaPhase 1
CN
13 Nov 2017
Relapsing acute myeloid leukemiaPhase 1
CN
13 Nov 2017
Advanced Malignant Solid NeoplasmPhase 1
CN
08 Feb 2014
Acute Myeloid LeukemiaPhase 1--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
86
syoycsarqn(gsvocxousw) = cghigikocr fnirgxmxxf (hpxwhcqynv )
Positive
29 May 2020
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Approval

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Regulation

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