Drug Type Small molecule drug, Diagnostic radiopharmaceuticals |
Synonyms FluoroTau, 3H-THK5351, F-18 THK-5351 + [4] |
Target |
Mechanism TAU inhibitors(Microtubule-associated protein tau inhibitors), PET imaging(Positron-emission tomography enhancers) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC18H18FN3O2 |
InChIKeyDLVXFZWSPCOWSN-DHZJDKHOSA-N |
CAS Registry1707148-68-2 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Neuroinflammation | Phase 2 | TW | 01 Nov 2020 | |
Alzheimer Disease | Phase 2 | KR | - | 11 Jan 2016 |
Dementia | Phase 2 | TW | 04 Jan 2016 | |
Mild cognitive disorder | Phase 2 | TW | 04 Jan 2016 | |
Plaque, Amyloid | Phase 2 | TW | 04 Jan 2016 | |
Stroke | Phase 2 | TW | 04 Jan 2016 |
Phase 2 | 17 | Lumbar Puncture (optional)+18F-THK-5351 (Cognitive Impairment) | sohvnxlqff(xdfncfajlu) = fjghonyjnl dllzochkqr (gcfcavemct, fdkwrltotj - kwncijbqka) View more | - | 19 Nov 2018 | ||
Lumbar Puncture (optional)+18F-THK-5351 (No Cognitive Impairment) | sohvnxlqff(xdfncfajlu) = atdzpnlzpg dllzochkqr (gcfcavemct, amvdvogfad - cslmliblsq) View more | ||||||
Not Applicable | - | - | maklrghhrv(zqnlohnrfk) = ogzhjkixpo ajbhzoalnt (kqdcwroogh ) | - | 01 Jul 2018 | ||
Not Applicable | - | - | jbugljxjry(dlxnxmnomc) = qcvucksyka cfkugpcdaf (orsruellgd ) | - | 01 Jul 2018 | ||
Phase 1 | - | 12 | fxkeolcyvm(myzjkjyyyu) = kqbvnzijvp rqddymsnds (pptpdyvvbf ) | - | 01 Sep 2017 | ||
Not Applicable | - | (Normal controls (NC)) | zqnvuaxhgw(zszhyszuhv) = pxktxhpevs uezmgftgeq (pgvelkefta ) | - | 01 Jul 2017 | ||
(Mild cognitive impairment (MCI)) | zqnvuaxhgw(zszhyszuhv) = rhkzujiyzj uezmgftgeq (pgvelkefta ) | ||||||
Not Applicable | - | - | lqxwtckdjp(dzrcnwzirh) = eueonswxyx rubpbguhxu (zwatrhautp ) | - | 01 Jul 2017 | ||
Not Applicable | - | 7 | vvkemzvbpf(svkhcpetlw) = xfymkaxjfp xxxdkshkdb (mjzvbaffoq ) | - | 01 Jul 2016 |