Drug Type Trispecific T-cell engager (TriTE) |
Synonyms |
Target |
Action inhibitors, stimulants |
Mechanism BCMA inhibitors(B-cell maturation protein inhibitors), CD3 stimulants(T cell surface glycoprotein CD3 stimulants), CD38 inhibitors(Lymphocyte differentiation antigen CD38 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
RegulationOrphan Drug (United States) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Refractory Multiple Myeloma | Phase 1 | India | 01 Nov 2023 | |
Refractory Multiple Myeloma | Phase 1 | Australia | 01 Nov 2023 | |
Refractory Multiple Myeloma | Phase 1 | United States | 01 Nov 2023 | |
Relapse multiple myeloma | Phase 1 | Australia | 01 Nov 2023 | |
Relapse multiple myeloma | Phase 1 | United States | 01 Nov 2023 | |
Relapse multiple myeloma | Phase 1 | India | 01 Nov 2023 |
NCT05862012 (ASH2024) Manual | Phase 1 | 14 | ISB 2001 5 μg/kg | (ealkowhxla) = None fexeuiuswe (ufmceygdno ) View more | Positive | 09 Dec 2024 |