Last update 30 Aug 2025

Semaxanib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Semaxanib (USAN/INN), Semoxind, NSC-696819
+ [5]
Action
antagonists
Mechanism
VEGFR1 antagonists(Vascular endothelial growth factor receptor 1 antagonists), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC15H14N2O
InChIKeyWUWDLXZGHZSWQZ-WQLSENKSSA-N
CAS Registry194413-58-6

External Link

KEGGWikiATCDrug Bank
D05819Semaxanib-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 3
United States
01 Nov 1999
Kaposi SarcomaPhase 3
United Kingdom
--
Non-Small Cell Lung CancerPhase 3
United States
--
AIDS-related Kaposi SarcomaPhase 2
United States
31 Aug 2001
Acute Myeloid LeukemiaPhase 2
United States
--
Acute Myeloid LeukemiaPhase 2
Germany
--
Acute Myeloid LeukemiaPhase 2
Switzerland
--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
33
pfdqeqohif(hlevaplirs) = nqegamfdnj hnxbbhrols (wsqrqwrcyt )
-
01 Feb 2009
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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