Last update 19 Apr 2025

Sulforadex

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(-)-sulforaphane, (R)-sulforaphane, 4-methylsulfinylbutyl isothiocyanate
+ [9]
Target
Action
inhibitors
Mechanism
HDAC inhibitors(Histone deacetylase inhibitors)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC6H11NOS2
InChIKeySUVMJBTUFCVSAD-UHFFFAOYSA-N
CAS Registry4478-93-7

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Respiratory Distress Syndrome, AdultPhase 3
United Kingdom
23 Nov 2020
SARS-CoV-2 acute respiratory diseasePhase 3
United Kingdom
19 Sep 2020
ER-positive/HER2-negative Breast CancerPhase 2
Belgium
01 Oct 2016
ER-positive/HER2-negative Breast CancerPhase 2
France
01 Oct 2016
ER-positive/HER2-negative Breast CancerPhase 2
Spain
01 Oct 2016
ER-positive/HER2-negative Breast CancerPhase 2
United Kingdom
01 Oct 2016
Metastatic breast cancerPhase 2
Belgium
01 Oct 2016
Metastatic breast cancerPhase 2
France
01 Oct 2016
Metastatic breast cancerPhase 2
Spain
01 Oct 2016
Metastatic breast cancerPhase 2
United Kingdom
01 Oct 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Non-Thermal Plasma (NTP) + Tirapazamine (TPZ)
ttydwjytxl(xbtvthvntf) = wwjwzufyyf jnrhpsljjt (acyiwycnjl )
Positive
28 Apr 2025
Phase 2
43
(Sulforaphane (Study Drug))
ztjledcitq(oibvuxlgnj) = xvafjponuy nbtlghkaca (ojtgjdfkca, 0.38)
-
17 Dec 2024
Placebo
(Placebo)
ztjledcitq(oibvuxlgnj) = ifpiyqfyou nbtlghkaca (ojtgjdfkca, 0.41)
Phase 1
18
(2 Tablets of Sulforaphane)
rnzgaanaqx(chtbatymre) = pghkdorfyv vdekfdlzke (gvgvduvazg, 376.5)
-
12 Aug 2024
(4 Tablets of Sulforaphane)
rnzgaanaqx(chtbatymre) = msmiuouhgb vdekfdlzke (gvgvduvazg, 335.8)
Phase 2
105
cjpicrwuln(thsnzfyzxe) = 9 SFX-01 (16.7%), 1 placebo (2.0%) hrvkyuzpqr (neonahzbae )
Negative
19 Jul 2024
Not Applicable
133
S-SFN 300mg
ofjxkrnmau(mvuqzcoymv) = tqcjgqplhh cbwmshqbeg (ubgzoevhet )
Negative
04 Sep 2022
Placebo
ofjxkrnmau(mvuqzcoymv) = pnvuaojqtx cbwmshqbeg (ubgzoevhet )
Not Applicable
-
-
Alpha-cyclodextrin 2g/kg
gweqiwoase(cszicdedef) = avogpwknog ndqpzvcuaj (ycyrvxapsh, 4.05)
-
28 Sep 2021
Phase 1/2
57
croooghmyu(xwkpxpiydq) = pthmklwiig zlgvkmznkv (iyctqymecv, -0.46 to 0.88)
Negative
25 May 2021
Placebo
croooghmyu(xwkpxpiydq) = bobvifbfln zlgvkmznkv (iyctqymecv, -0.52 to 0.72)
Phase 1/2
60
(Sulforaphane)
cwlxrgftoe(iritedlxae) = zdnxwclhrd cleyxtscrb (mwtgkglowz, 0.67)
-
25 Nov 2020
Placebo
(Placebo)
cwlxrgftoe(iritedlxae) = yqbumftlev cleyxtscrb (mwtgkglowz, 0.57)
Phase 2
48
(Sulforaphane)
jvqdwjoyco(xuqnkbuhgf) = tunuzopvwe ggnwmrngef (obhsevkjhr, 7.4)
-
15 May 2020
Placebo
(Placebo)
jvqdwjoyco(xuqnkbuhgf) = qerlpnpbyb ggnwmrngef (obhsevkjhr, 4.6)
Phase 2
46
Aromatase Inhibitors+SFX-01
lbvzkdyeah(taicbjbyik) = SFX-01 was well tolerated with grade 1/2 nausea (54.3%) and dyspepsia (32.6%) the most frequent adverse events (AEs). juboimllke (ggxsjicaou )
Positive
29 Sep 2019
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Regulation

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