Last update 24 Jun 2024

Enarodustat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Enarodustat (JAN), 恩那度司他, JTZ-951
+ [4]
Target
Mechanism
HIF-PHs inhibitors(Hypoxia-inducible factor prolyl hydroxylase inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
JP (25 Sep 2020),
Regulation-
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Structure

Molecular FormulaC17H17ClN4O4
InChIKeyBPZAJOSLAXGKFI-UHFFFAOYSA-N
CAS Registry1262131-60-1

External Link

KEGGWikiATCDrug Bank
D11523-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
chronic renal failure anemia
KR
17 Nov 2022
Anemia of renal disease
JP
25 Sep 2020
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anemia in chronic kidney diseasePhase 1
US
01 May 2013
Kidney Failure, ChronicPhase 1
US
01 May 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Anemia in chronic kidney disease
hemoglobin | erythropoietin
22
gsagcdotee(lsjdtbgbhz) = The results of reticulocyte count, hematocrit level and red blood cells in terms of changes from baseline at Week 6 were similar to that in hemoglobin agfgthxrqx (kpqbnenzzx )
Positive
21 May 2015
Phase 1
hemoglobin | transferrin saturation | ferritin ...
-
JTZ-951 2 mg
tltdxvrlgj(zwjlgibnjr) = dmihpazqgx pzytblrcdr (hfcoojnuco )
Positive
21 May 2015
JTZ-951 10 mg
tltdxvrlgj(zwjlgibnjr) = gioijpsevd pzytblrcdr (hfcoojnuco, -0.7 to 2.3)
Not Applicable
Anemia in chronic kidney disease
Maintenance
hemoglobin | Erythropoiesis Stimulating Agents (ESAs) | iv iron ...
40
hjjufjbzig(avtpyeggmr) = The results of reticulocyte count, hematocrit level and red blood cells in terms of changes from baseline at week 8 were similar to that in hemoglobin xxsvmvfsqg (kpuamptjpb )
Positive
21 May 2015
JTZ-951 3 mg
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Regulation

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