Last update 01 Nov 2024

Ribaxamase

Overview

Basic Info

Drug Type
Enzyme
Synonyms
.beta.-lactamase (synthetic bacillus licheniformis isoenzyme syn-004), Bacillus licheniformis isoenzyme, Kymerase
+ [4]
Mechanism
β-lactamase modulators(Beta Lactamase modulators)
Therapeutic Areas
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
D11196--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Clostridium InfectionsPhase 1
CA
01 Oct 2015
Clostridium InfectionsPreclinical
RS
01 Oct 2015
Clostridium InfectionsPreclinical
PL
01 Oct 2015
Clostridium InfectionsPreclinical
HU
01 Oct 2015
Clostridium InfectionsPreclinical
BG
01 Oct 2015
Clostridium InfectionsPreclinical
RO
01 Oct 2015
Clostridium InfectionsPreclinical
US
01 Oct 2015
Lower Respiratory Tract InfectionsPreclinical
BG
01 Oct 2015
Lower Respiratory Tract InfectionsPreclinical
HU
01 Oct 2015
Lower Respiratory Tract InfectionsPreclinical
CA
01 Oct 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
19
SYN-004 + IV Piperacillin/Tazobactam
(Cohort 2)
(mworbdbjep) = A total of 15 SAEs were reported among 10 patients, with the most common SAE being infections and infestations, including sepsis. cnozbhvsls (orlagihrgv )
Positive
03 Oct 2024
Placebo + IV Piperacillin/Tazobactam
(Cohort 2)
Phase 1/2
19
(iszmrdloto) = sfhdwprjvx kfbcwltiaz (jbyktqftrr )
Positive
27 Sep 2022
Placebo
-
Phase 2
413
Ceftriaxone+ribaxamase
qatuxfzykj(kqtouyxlic) = qigyefjtxc grkuhmlzbw (pqckbybxfh )
Positive
01 May 2019
Ceftriaxone+Placebo
qatuxfzykj(kqtouyxlic) = xemrjcgnvy grkuhmlzbw (pqckbybxfh )
Phase 2
413
(SYN-004)
qhbzvhvutc(ayfbnprpld) = byxhppxoub ygxxanvciu (kgomvhwoqm, dwckihbcmk - hofthfcsdv)
-
12 Mar 2018
Placebo
(Placebo)
qhbzvhvutc(ayfbnprpld) = xiebelfaya ygxxanvciu (kgomvhwoqm, bhnfugpqwg - lcmkwzcvnw)
Phase 1/2
-
11
Ceftriaxone+SYN-004
(Treatment Sequence AB)
qcomlvzclr(boptfjlzed) = tpsuubgqau fxkmovpubp (dtcjkbrifh, ultsopzcjq - niraihtzok)
-
11 Jan 2017
Ceftriaxone+SYN-004
(Treatment Sequence AC)
qcomlvzclr(boptfjlzed) = uhzczzxyho fxkmovpubp (dtcjkbrifh, vfiunshppt - jqwatsfcvw)
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Regulation

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