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Last update 24 Mar 2025
Cotosudil
Last update 24 Mar 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms H-1129, WP 1303 |
Target |
Action inhibitors |
Mechanism HSP90 inhibitors(Heat shock 90kDa proteins inhibitors), ROCK2 inhibitors(Rho-associated protein kinase 2 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Molecular FormulaC16H21N3O2S |
InChIKeyOIJDBECSPSHUGA-CYBMUJFWSA-N |
CAS Registry1258833-31-6 |
Related
4
Clinical Trials associated with CotosudilJPRN-JapicCTI-194923
A combination study on WP-1303 or placebo and timolol ophthalmic solution in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH)
JPRN-JapicCTI-194921
A combination study on WP-1303 or placebo and latanoprost ophthalmic solution in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH).
JPRN-JapicCTI-194920
A comparison study on WP-1303 and ripasudil ophthalmic solution in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH).
100 Clinical Results associated with Cotosudil
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100 Translational Medicine associated with Cotosudil
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100 Patents (Medical) associated with Cotosudil
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100 Deals associated with Cotosudil
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Glaucoma, Open-Angle | Phase 3 | Japan | 06 Sep 2019 | |
| Glaucoma | Phase 2 | Japan | 01 Jul 2018 | |
| Choroidal Neovascularization | Preclinical | Japan | 07 May 2017 | |
| Choroidal Neovascularization | Preclinical | - | 07 May 2017 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 2 | - | H-1129 eye drops 0.5% | xhtqgwlpqk(ypgvtmnaue) = pudwocvpkg kuldjffarp (ipwsbmdkhm ) View more | Positive | 07 May 2017 | ||
H-1129 eye drops 2% | rnwncbtdku(zuvxiigloh) = xiiejrqkip ixbgnrctcy (stsxvmshxb ) |
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