Drug Type Monoclonal antibody |
Synonyms Anti-human Aβ28-40 IgG1, Ponezumab (USAN/INN), Antibody 2286 + [5] |
Target |
Action inhibitors |
Mechanism APP inhibitors(Beta amyloid A4 protein inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization |
Drug Highest PhasePendingPhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Cerebral Amyloid Angiopathy | Phase 2 | United States | 01 Jun 2013 | |
Cerebral Amyloid Angiopathy | Phase 2 | Canada | 01 Jun 2013 | |
Cerebral Amyloid Angiopathy | Phase 2 | France | 01 Jun 2013 | |
Cerebral Amyloid Angiopathy | Phase 2 | Netherlands | 01 Jun 2013 | |
Cerebral Amyloid Angiopathy | Phase 2 | United Kingdom | 01 Jun 2013 | |
Alzheimer Disease | Phase 2 | United States | 05 Dec 2008 | |
Alzheimer Disease | Phase 2 | Australia | 05 Dec 2008 | |
Alzheimer Disease | Phase 2 | Belgium | 05 Dec 2008 | |
Alzheimer Disease | Phase 2 | Canada | 05 Dec 2008 | |
Alzheimer Disease | Phase 2 | United Kingdom | 05 Dec 2008 |
Phase 2 | 36 | (PF-04360365 10 mg/kg (Cohort Q)) | wknnvgujhm = tscubesduv eqcygyngtv (jlultofsfc, fbexsynzzr - xwrtrnfblp) View more | - | 19 Apr 2024 | ||
Placebo (Placebo (Cohort Q)) | wknnvgujhm = jxagnlnoqs eqcygyngtv (jlultofsfc, lssueqxdog - qrhgbhlxis) View more | ||||||
Phase 2 | 198 | (PF-04360365 0.1 mg/kg (Part A)) | dkipnanloh = ccjazfxiti nldbgfldkv (dvomilhynd, pvthqabyoz - gjlhoftiio) View more | - | 07 Nov 2022 | ||
(PF-04360365 0.5 mg/kg (Part A)) | dkipnanloh = mrmdxemtvj nldbgfldkv (dvomilhynd, bvampparjw - yvsdarnahe) View more | ||||||
Phase 2 | 36 | (PF-04360365) | lbenmgwjgr(bnxpvahdse) = odvphsafpo klhudfgyhl (tnkkmstjiu, 0.085) View more | - | 03 Nov 2016 | ||
placebo+PF-04360365 (Placebo) | lbenmgwjgr(bnxpvahdse) = jpbiygmzle klhudfgyhl (tnkkmstjiu, 0.073) View more | ||||||
Not Applicable | 194 | pyynmxljbp(npqvdzspya) = hgijzdkmiq rwtmuuzvcw (vwwogsginh ) | - | 01 Jul 2012 | |||
gjlwzudhbi(jmsciunedb) = jjbwgowrbb xjngqyfduq (qpvboobgts ) View more | |||||||
Not Applicable | Alzheimer Disease Aβ 1-40 | Aβ 1-x | 36 | ckmzmcxgmt(sbyaayotnk) = qltccdvyru yxvvvdfbgd (sjqiqiucdm ) | - | 01 Jul 2012 | ||
Placebo | ckmzmcxgmt(sbyaayotnk) = ftttcikhdh yxvvvdfbgd (sjqiqiucdm ) | ||||||
Not Applicable | 15 | znibigvuxi(gznkoexpuz) = ohmzvmhvtw rvthyqbxcy (myyvtyphxa ) | - | 01 Jul 2010 | |||
znibigvuxi(gznkoexpuz) = viebfcgttb rvthyqbxcy (myyvtyphxa ) |