Last update 01 Nov 2024

Afabicin diolamine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Afabicin, Debio-1452-prodrug
+ [5]
Target
Mechanism
MECR inhibitors(Enoyl-acyl-carrier protein reductase inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC27H38N5O9P
InChIKeyRLXLAXQJCXOHNX-OJYIHNBOSA-N
CAS Registry1518800-36-6

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bone and joint infectionsPhase 2
UA
20 Feb 2019
Bone and joint infectionsPhase 2
GE
20 Feb 2019
Bone and joint infectionsPhase 2
US
20 Feb 2019
Bone and joint infectionsPhase 2
AR
20 Feb 2019
Skin and skin structure infectionsPhase 2
US
01 May 2015
Skin Diseases, BacterialPhase 2
US
01 May 2015
Complicated skin and soft tissue infectionPhase 2
US
02 Apr 2015
Skin Diseases, InfectiousPhase 2--
Soft Tissue InfectionsPhase 2--
Soft Tissue InfectionsPhase 2--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
330
(Debio 1450 80 mg/120 mg BID)
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-
13 Nov 2019
(Debio 1450 160 mg/240 mg BID)
hxelfqreyf(wrzuhmddpx) = zkpkwnvzvh vklvqdnpfh (byogmhwzin, mldywhrbkx - mhowdfrqgw)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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