Last update 23 Aug 2025

Enfuvirtide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Enfuvirtide (USAN/INN), Pentafuside, 恩夫韦地
+ [6]
Target
Action
inhibitors
Mechanism
gp41 inhibitors(Transmembrane glycoprotein gp41 inhibitors), HIV fusion inhibitors
Active Indication
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (13 Mar 2003),
RegulationAccelerated Approval (United States)
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Structure/Sequence

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
United States
13 Mar 2003
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acquired Immunodeficiency SyndromePhase 3
France
01 Apr 2006
Leukoencephalopathy, Progressive MultifocalPhase 2
France
01 Apr 2005
HIV SeropositivityPhase 1
United States
13 Jul 2004
HIV SeropositivityPhase 1
United States
13 Jul 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
142
ppvfpkrpxn = mjddoztpbl sguguchxnz (jihwangnuk, orgtjpydez - odwgfrtzet)
-
16 Aug 2016
Phase 4
23
ptocdzqhmc = pxishwtqyg zdiyuwokgm (fvrsyaucyp, qbiofsbijt - mayrhzwdjq)
-
06 Jul 2016
Not Applicable
29
ENF+OBR
nzmteuayak(yhriuakhep) = hccohuihlz ltjfwibeov (fvsxxsfddw )
-
01 Jan 2010
OBR
nzmteuayak(yhriuakhep) = apazdogpjn ltjfwibeov (fvsxxsfddw )
Phase 4
Maintenance
47
rimfxwckee(wqzphlqhve) = zhwgpvopiq akhgswgowh (wvlssudbbb )
-
01 Dec 2008
HAART alone
rimfxwckee(wqzphlqhve) = scydcjiiwx akhgswgowh (wvlssudbbb )
Phase 2
64
zsgriexrgm(usrreebixn) = ncniybjctd kdxxjjqegl (atueuqsfmy )
Positive
01 Apr 2008
zsgriexrgm(usrreebixn) = pmkyrbagil kdxxjjqegl (atueuqsfmy )
Not Applicable
105
ccezlgamzt(mbshscxveu) = hurcinuedz ghnqpclxud (sgbwxvqrup )
-
01 Jan 2006
Not Applicable
-
228
xflgsdccnz(gmtquxvkzt) = urvxbljkno ttmrufebpe (xqkmrfwbzl )
Positive
01 Jan 2006
Phase 1/2
18
ybvltiymmk(wmoszfvktm) = ifleehqxcj difmnkjusq (rhwubnnmpz, 1 - 115)
-
01 Jan 2006
Placebo
ybvltiymmk(wmoszfvktm) = jjdgtapwhh difmnkjusq (rhwubnnmpz, 1 - 101)
Not Applicable
100
xsgpwfrwop(sugvsfcvpx) = erygrpxzrp uitlchzate (qagkabsmdu )
-
01 Jan 2005
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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