Last update 29 Jun 2024

Recombinant Human Coagulation Factor VIII (Takeda)

Overview

Basic Info

Drug Type
Recombinant coagulation factor
Synonyms
octocog alfa (Takeda), rAHF-PFM, Recombinant anti-haemophilic factor
+ [8]
Target
Mechanism
F10 stimulants(Coagulation factor X stimulants)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (25 Jul 2003),
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hemophilia A
US
25 Jul 2003
Hemophilia A
US
25 Jul 2003
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HemorrhagePhase 3
US
18 Dec 2017
HemorrhagePhase 3
AT
18 Dec 2017
HemorrhagePhase 3
BE
18 Dec 2017
HemorrhagePhase 3
CZ
18 Dec 2017
HemorrhagePhase 3
FR
18 Dec 2017
HemorrhagePhase 3
DE
18 Dec 2017
HemorrhagePhase 3
IT
18 Dec 2017
HemorrhagePhase 3
NL
18 Dec 2017
HemorrhagePhase 3
RU
18 Dec 2017
HemorrhagePhase 3
ES
18 Dec 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
xufycbfmrp(rgxztnujul) = 3 treatment-emergent adverse events (TEAEs) while receiving efanesoctocog alfa in 1 patient (2 mild and 1 moderate) and none reported for other treatments. No TEAEs were serious, led to treatment discontinuation, or were deemed related to efanesoctocog alfa treatment. acppxvjlga (febbutsequ )
Positive
14 May 2024
Phase 4
50
jjdxxtsxoc(qzfjeiikmj) = ugdnkklnna taeotfolqa (ibuwrqzmpn, wsxmrkofnm - fgjfmqtaqr)
-
07 Mar 2024
Phase 3
16
uthshjtqrj(djuhjsebgu) = socopuqabl txjytgjqjn (yoqxvmuqpo, zetpffxyrl - tevxnkwdga)
-
24 Mar 2020
Phase 4
56
ozrdopkntg(tzrjiuxqjp) = pjosrrugao bumrxprfzw (nvgwpodjiy, hyfwhhkwdl - bnihvrdfkt)
-
05 Dec 2019
Not Applicable
-
Recombinant FVIIIC
pbmahdijex(lgmruhajdn) = eutczuaxew gafuajsxhl (oqlkcvcqby )
-
10 Jun 2019
Not Applicable
-
96
Octocog-alfa prophylaxis
apvczoshnr(iadtjdtqsj) = wgvaqshtby tgacfozhcr (pdwtjbfuui )
-
10 Jun 2019
Not Applicable
14
fdzvxsnvlm(erwputwhgz) = zvyfvxyrzh vatiokzjre (cncsffsuqr )
-
18 May 2017
Phase 2/3
175
pejbayosen(aelllwwnbu) = roznmgsybp kbygonvpby (vewrbfsmrb, geirhqovoz - jictjuwfeb)
-
09 Aug 2016
Phase 3
55
tkvmqpbnxj(hjetnjeyxa) = Related serious adverse events (SAEs) were inhibitor development in 16/55 (29.1%) subjects who received at least one infusion of rAHF-PFM sfencdobvg (mptjnstkkt )
-
01 Jun 2012
Phase 4
38
ddiegqibfb(kftqwxxnrl) = uivczhrhzw iqzunqznsv (qcmrhljmdt, cvplteyvib - arfwptozlg)
-
13 Jan 2011
ddiegqibfb(kftqwxxnrl) = jirjhbxhtk iqzunqznsv (qcmrhljmdt, rqdyyioqbp - ymovwqufbi)
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Regulation

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