Last update 19 Jun 2024

Aflibercept/Nesvacumab

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
Aflibercept/Ang2-antibody, Ang2 antibody/Eylea, Ang2-antibody/aflibercept
+ [6]
Mechanism
Ang2 inhibitors(Angiopoietin-2 inhibitors), PGF inhibitors(Placental Growth Factor inhibitors), VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic macular oedemaPhase 2
US
02 Mar 2016
Dystrophy, MacularPhase 2--
Wet Macular DegenerationPhase 2
US
-
Choroidal NeovascularizationPhase 1
US
01 Nov 2014
Wet age-related macular degenerationPhase 1
US
01 Nov 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
302
(REGN910-3 (3 mg: 2 mg))
kkqryjeqwl(hqcdmdmyxa) = uipiayiynd wjldfsxkil (uwzfvsrogh, wwnkbybkar - icdxkctelq)
-
03 Oct 2018
(REGN910-3 (6 mg:2 mg))
kkqryjeqwl(hqcdmdmyxa) = jivmxavydd wjldfsxkil (uwzfvsrogh, kbfmkdpxnf - dngaqmgwbd)
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Approval

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Regulation

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