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Last update 23 Jan 2025
Aflibercept/Nesvacumab
Last update 23 Jan 2025
Overview
Basic Info
Drug Type Fusion protein |
Synonyms Aflibercept/Ang2-antibody, Ang2 antibody/Eylea, Ang2-antibody/aflibercept + [6] |
Target |
Mechanism Ang2 inhibitors(Angiopoietin-2 inhibitors), PGF inhibitors(Placental Growth Factor inhibitors), VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 10152848H
The sequence is quoted from: *****
Sequence Code 10152862L
The sequence is quoted from: *****
Sequence Code 4715606
The sequence is quoted from: *****
Related
3
Clinical Trials associated with Aflibercept/NesvacumabNCT02713204
A Randomized, Double-Masked, Active-Controlled Phase 2 Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal REGN910-3 in Patients With Neovascular Age-Related Macular Degeneration
NCT02712008
A Randomized, Double-Masked, Active-Controlled, Phase 2 Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal REGN910-3 in Patients With Diabetic Macular Edema
NCT01997164
An Open-Label, Dose-Escalation Study of the Safety and Tolerability of Intravitreal (IVT) REGN910-3 and IVT REGN910 in Patients With Either Neovascular AMD or DME
100 Clinical Results associated with Aflibercept/Nesvacumab
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100 Translational Medicine associated with Aflibercept/Nesvacumab
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100 Patents (Medical) associated with Aflibercept/Nesvacumab
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100 Deals associated with Aflibercept/Nesvacumab
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Diabetic macular oedema | Phase 3 | US | 02 Mar 2016 | |
| Diabetic macular oedema | Phase 3 | US | 02 Mar 2016 | |
| Wet Macular Degeneration | Phase 3 | US | - | |
| Dystrophy, Macular | Phase 2 | - | - | |
| Choroidal Neovascularization | Discovery | US | 01 Nov 2014 | |
| Wet age-related macular degeneration | Discovery | US | 01 Nov 2014 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 2 | 302 | (REGN910-3 (3 mg: 2 mg)) | tfqxolcfel(tflpapfrzl) = ghzqzhtyrb pivldfxzan (jmosiwtjyl, mbknaykatq - xyikdeulgw) View more | - | 03 Oct 2018 | ||
(REGN910-3 (6 mg:2 mg)) | tfqxolcfel(tflpapfrzl) = bgpuvyegnu pivldfxzan (jmosiwtjyl, ncneoefedt - xdlbsypkqn) View more | ||||||
Phase 1 | - | (bznezmrgxx) = 2 patients [10%]; unrelated to study drug/procedure mdkmtyrajj (jtdtnrlxek ) View more | Positive | 16 Oct 2016 |
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