Drug Type Small molecule drug |
Synonyms 依奉阿克, CT-1139, TQ B3139 |
Target |
Mechanism ALK inhibitors(Anaplastic lymphoma kinase inhibitors), ROS1 inhibitors(Proto-oncogene tyrosine-protein kinase ROS inhibitors), c-Met inhibitors(Hepatocyte growth factor receptor inhibitors) |
Therapeutic Areas |
Active Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date CN (11 Jun 2024), |
RegulationSpecial Review Project (CN) |
Molecular FormulaC24H26Cl2FN5O2 |
InChIKeyBVGDAZBTIVRTGO-UONOGXRCSA-N |
CAS Registry1621519-26-3 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
ALK positive Non-Small Cell Lung Cancer | CN | 11 Jun 2024 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
MET gene amplification Non-small Cell Lung Cancer | Phase 2 | CN | 11 Aug 2020 | |
Advanced Malignant Solid Neoplasm | Phase 1 | CN | 01 Feb 2021 | |
Advanced cancer | Phase 1 | CN | 12 Jul 2017 |
Phase 3 | ALK positive Non-Small Cell Lung Cancer First line | 264 | rpranjbfeb(kvhxqhjnqe) = lofzkdxige quhyougmbp (owgxnnynqa ) View more | Positive | 14 Aug 2023 | ||
rpranjbfeb(kvhxqhjnqe) = zqtxhtldyt quhyougmbp (owgxnnynqa ) View more | |||||||
Phase 3 | ALK positive Non-Small Cell Lung Cancer First line | 264 | Envonalkib 600mg (overall) | ycdgwxcftk(rivpijvdtt) = csdwigxxzq rpywjilemu (ohevflfioj ) View more | Superior | 03 Dec 2022 | |
(overall) | ycdgwxcftk(rivpijvdtt) = tebjohpqxr rpywjilemu (ohevflfioj ) View more | ||||||
Phase 1 | 63 | rozkiwkohj(ucamehgdrv) = 76.1% vethhtazeg (pimyohvyoa ) View more | Positive | 05 Aug 2022 |