Delving into the Latest Updates on NHL35700 with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

NHL 35700, NHL-35700, NHL35700

Target

PDE10A

Mechanism

PDE10A inhibitors(Phosphodiesterase 10A inhibitors)

Therapeutic Areas

Other Diseases

Active Indication

Schizophrenia

Inactive Indication-

Originator Organization

Jiangsu Nhwa Pharmaceutical Co., Ltd.Shanghai Shujing Biotechnology Co., Ltd.

Active Organization

Jiangsu Nhwa Pharmaceutical Co., Ltd.

Inactive Organization-

Drug Highest PhasePhase 2

First Approval Date-

Regulation-

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Primary objective: To evaluate the effectiveness of NHL35700 in the treatment of schizophrenia using the active drug risperidone and placebo as controls. Secondary objective: To evaluate the safety of NHL35700 in patients with schizophrenia. Exploratory objective: To evaluate the pharmacokinetic (PK) characteristics of NHL35700.

Start Date11 Apr 2024

Sponsor / Collaborator

Shanghai Shujing Biotechnology Co., Ltd.

[+1]

CTR20230273 / CompletedPhase 1

评价NHL35700片在中国健康受试者中的药代动力学特征、安全性和耐受性的开放、单次给药研究

[Translation] An open-label, single-dose study to evaluate the pharmacokinetic characteristics, safety, and tolerability of NHL35700 tablets in healthy Chinese subjects

评价中国健康受试者单次口服NHL35700后原药和其代谢产物的药代动力学（PK）特性、安全性和耐受性。探索性目的：如数据允许，探索NHL35700单次给药的暴露与不良事件之间的关系。以上研究不作为临床报告的必要内容。

[Translation]

To evaluate the pharmacokinetic (PK), safety, and tolerability of NHL35700 and its metabolites after a single oral administration in healthy Chinese subjects. Exploratory purpose: If data permit, explore the relationship between exposure and adverse events of a single dose of NHL35700. The above studies are not necessary for clinical reports.

Start Date22 Feb 2023

Sponsor / Collaborator

Shanghai Shujing Biotechnology Co., Ltd.

[+1]

100 Clinical Results associated with NHL35700

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100 Translational Medicine associated with NHL35700

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100 Patents (Medical) associated with NHL35700

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100 Deals associated with NHL35700

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