Last update 01 Nov 2024

BI-905681

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Target
LRP5
Mechanism
LRP5 inhibitors(LDL receptor related protein 5 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Advanced Malignant Solid Neoplasm
Originator Organization
Boehringer Ingelheim GmbHBoehringer Ingelheim GmbH
Active Organization-
Inactive Organization
Boehringer Ingelheim GmbHBoehringer Ingelheim GmbH
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with BI-905681
NCT04147247 / CompletedPhase 1
An Open-label, Phase I Trial to Determine the Maximum-tolerated Dose and Investigate Safety, Pharmacokinetics and Efficacy of BI 905681 Administered Intravenously in Patients With Advanced Solid Tumours
100 Clinical Results associated with BI-905681
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100 Translational Medicine associated with BI-905681
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100 Patents (Medical) associated with BI-905681
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100 Deals associated with BI-905681
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
US
Boehringer Ingelheim GmbHBoehringer Ingelheim GmbH
23 Dec 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT04147247 (CTgov)
Phase 1
Advanced Malignant Solid Neoplasm
21
(1.0 Milligram/Kilogram BI 905681)
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-
29 Nov 2023
(2.5 Milligram/Kilogram BI 905681)
lnbejvwpuu(bvegmlyaei) = zoruqpyxxi piccvqrsjs (udvwmqveds, amgcvyrncz - zqsrqnncng)
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Clinical Trial

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Approval

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Regulation

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