Drug Type Small molecule drug |
Synonyms ACNU, Nimustine, Nimustine hydrochloride (JAN) + [5] |
Target |
Mechanism DNA inhibitors(DNA inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date JP (22 May 1979), |
Regulation- |
Molecular FormulaC9H14Cl2N6O2 |
InChIKeyKPMKNHGAPDCYLP-UHFFFAOYSA-N |
CAS Registry55661-38-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01059 | Nimustine Hydrochloride |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Chronic Lymphocytic Leukemia | CN | 25 Jul 2002 | |
Philadelphia chromosome positive chronic myelogenous leukemia | CN | 25 Jul 2002 | |
Brain Cancer | JP | 22 May 1979 | |
Chronic leukemia | JP | 22 May 1979 | |
Colorectal Cancer | JP | 22 May 1979 | |
Liver Cancer | JP | 22 May 1979 | |
Lung Cancer | JP | 22 May 1979 | |
Lymphoma | JP | 22 May 1979 | |
Stomach Cancer | JP | 22 May 1979 |
Phase 2 | 21 | qfhhermwem(tsogzbzpme) = lqhbybithv xkertjvwwz (nigoazjkhj ) View more | Positive | 02 Jun 2022 | |||
Not Applicable | Recurrent Glioblastoma Third line | 35 | hwlgybdsrd(vgplfszoko) = iheuwxpjhn ydosebqeft (pushpwzbee ) View more | Positive | 20 May 2008 | ||
Not Applicable | 151 | dofltscgii(xtrscmjhrl) = lzohackarp daauktwvnr (jkxtvgyhfs ) | Positive | 20 May 2008 |