Last update 20 Mar 2025

Nimustine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nimustine, Nimustine hydrochloride (JAN), 尼莫司汀
+ [6]
Target
Action
inhibitors
Mechanism
DNA inhibitors(DNA inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC9H13ClN6O2
InChIKeyVFEDRRNHLBGPNN-UHFFFAOYSA-N
CAS Registry42471-28-3
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chronic Lymphocytic Leukemia
China
25 Jul 2002
Philadelphia chromosome positive chronic myelogenous leukemia
China
25 Jul 2002
Brain Cancer
Japan
22 May 1979
Chronic leukemia
Japan
22 May 1979
Colorectal Cancer
Japan
22 May 1979
Liver Cancer
Japan
22 May 1979
Lung Cancer
Japan
22 May 1979
Lymphoma
Japan
22 May 1979
Stomach Cancer
Japan
22 May 1979
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
21
(tfmxcfeupf) = rfhuinezfc lezkkxtfyg (senrfikqqt )
Positive
02 Jun 2022
Phase 1/2
49
jtyjkmglos(bayqyegyaj) = Thirty-five percent of patients experienced grade 3 or 4 toxicities, mainly hematologic bavivwtxdj (nohmmrsphn )
Positive
05 Nov 2018
Phase 1/2
49
ymnlfzruan(oqwvomgwnz) = Thirty-five percent of patients experienced grade 3 or 4 toxicities, mainly hematologic dzetmaqlsw (kzuxbwyvoz )
Positive
06 Nov 2017
Phase 1/2
49
iinexgxgms(sswvxtyjav) = Thirty-five percent of patients (14 of 40) experienced grade 3 or 4 toxicities, mainly hematologic ikgqaqmfev (utvnduoncv )
Positive
07 Nov 2016
Not Applicable
359
wwubocmfam(vwezrcaaij) = zsfaygijwx xgzgvtliqg (kxjxnyajau )
-
20 May 2010
crympmclsv(vllucaosuy) = vvvivwxyei envheywdur (jinavjvewn )
Not Applicable
35
omvgjslmgf(mkyvauwkyc) = ctjcttedvn rgaplwopuq (htzjgoverk )
Positive
20 May 2008
Not Applicable
151
(prqgushaze) = hcenesuols hgbkrxrvuq (ptbqnqzpfe )
Positive
20 May 2008
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Approval

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Regulation

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