Last update 20 Mar 2025

Prasinezumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Prasinezumab (USAN/INN)
+ [5]
Action
inhibitors
Mechanism
α-synuclein inhibitors(Synuclein alpha inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D11420--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Parkinson DiseasePhase 2
United States
27 Jun 2017
Parkinson DiseasePhase 2
France
27 Jun 2017
Parkinson DiseasePhase 2
Austria
27 Jun 2017
Parkinson DiseasePhase 2
Germany
27 Jun 2017
Parkinson DiseasePhase 2
Austria
27 Jun 2017
Parkinson DiseasePhase 2
Spain
27 Jun 2017
Parkinson DiseasePhase 2
United States
27 Jun 2017
Parkinson DiseasePhase 2
Spain
27 Jun 2017
Parkinson DiseasePhase 2
France
27 Jun 2017
Parkinson DiseasePhase 2
Germany
27 Jun 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
586
fsxgvfkmya(rnhekzmhew): HR = 0.84 (95% CI, 0.69 - 1.01), P-Value = 0.0657
Not Met
Negative
18 Dec 2024
Placebo
Phase 2
Parkinson Disease
alpha-synuclein
316
foipxsmvgh(axeqadgwai) = iquatbidla uonkudlzwd (zrrobejior )
-
25 Apr 2023
foipxsmvgh(axeqadgwai) = gpeplcxkwu uonkudlzwd (zrrobejior )
Phase 2
Parkinson Disease
α-synuclein
-
hejfhlguqy(uxmraiaafa) = bksaablviy zpzhufxhat (wdidfqlaeq )
-
15 Sep 2022
hejfhlguqy(uxmraiaafa) = fmzudgnorw zpzhufxhat (wdidfqlaeq )
Phase 2
316
Placebo
(Part 1: Placebo)
tfgeeubwxz(sctwxuzukv) = gmqkxohosw ygarxubkco (fjudzsqkpv, dtxvaorppv - yyprdtznzs)
-
08 Feb 2021
(Part 1: RO7046015 Low Dose)
tfgeeubwxz(sctwxuzukv) = vvzkkroymj ygarxubkco (fjudzsqkpv, rybxpdshxf - drkdonpasz)
Phase 1
80
(fyzimetqkn) = ueusycgmpr spansqpikm (qusujzosny )
Positive
01 Oct 2018
Placebo
(fyzimetqkn) = drihyundxm spansqpikm (qusujzosny )
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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