Last update 26 Dec 2024

Danburstotug

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
IMC-001, STI-3031, STI-A1015
Target
Mechanism
PDL1 inhibitors(Programmed death-ligand 1 inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects), Immunomodulators
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cancer with a high tumour mutational burdenPhase 2-01 Jun 2024
Locally Advanced Malignant Solid NeoplasmPhase 2-01 Jun 2024
Diffuse Large B-Cell LymphomaPhase 2-01 Mar 2023
Gallbladder NeoplasmsPhase 2-01 Mar 2023
Intrahepatic CholangiocarcinomaPhase 2-01 Mar 2023
Peripheral T-Cell LymphomaPhase 2-01 Mar 2023
Relapsed Solid NeoplasmPhase 2-01 Jun 2021
Extranodal NK-T-Cell LymphomaPhase 2
KR
28 Jul 2020
Solid tumorPhase 1
KR
01 Nov 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
15
infxngaulv(gielzxszbb) = bnvmxdaich ihvrsylqva (hivxohgtay )
Positive
09 Jun 2023
Phase 2
Gastrointestinal Neoplasms
Adjuvant
Microsatellite Stable (MSS) | PD-L1 Expression
50
fkzamaokwr(sifttmqqxf) = Although there was no major pathologic response, 51% of pts showed various degree of tumor necrosis or fibrosis and 7 pts (15%) had residual viable tumor cells less than 50%. skfipptivf (byonkhgavh )
Positive
14 Apr 2023
(metabolic response-evaluable pts)
Phase 2
13
gfecjqjmwh(mrtvphokjk) = tbdelqgkat weqowncggx (zjhvwkpsfd )
Positive
04 Dec 2022
Phase 1
15
hhnsumdefj(wrkrbsyscj) = nspbfjojbg vscphmnatq (dseeapfuqv )
Positive
01 Dec 2021
Phase 2
14
yvfxczvkaj(myfndfqfal) = mtjsilbtss oxzrqhjtll (nktleqkjru )
-
25 May 2020
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Approval

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Regulation

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