Last update 21 Nov 2024

Brazikumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-IL-23-MAb (Amgen), Brazikumab (USAN/INN), Immunoglobulin g2, anti-(human interleukin 23) (human monoclonal medi2070 heavy chain), disulfide with human monoclonal medi2070 .lambda.-chain, dimer
+ [3]
Target
Mechanism
IL-23 inhibitors(Interleukin-23 inhibitors)
Active Indication
Originator Organization
Active Organization
Drug Highest PhasePreclinical
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
D10912Brazikumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Crohn DiseasePhase 2
IT
07 Dec 2018
Crohn DiseasePhase 2
ES
07 Dec 2018
Crohn DiseasePhase 2
IL
07 Dec 2018
Crohn DiseasePhase 2
KR
07 Dec 2018
Crohn DiseasePhase 2
CA
07 Dec 2018
Crohn DiseaseDiscovery
CA
07 Dec 2018
Crohn DiseaseDiscovery
ES
07 Dec 2018
Crohn DiseaseDiscovery
IL
07 Dec 2018
Crohn DiseaseDiscovery
IT
07 Dec 2018
Crohn DiseaseDiscovery
KR
07 Dec 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
104
uhtslaexaf(rkwdztrvin) = Common TEAEs included nasopharyngitis and headache fchvilznnj (okknomjqcx )
Positive
20 Dec 2023
Placebo
Phase 2
121
placebo
(Placebo)
uikrvgeugv(nkowablnuw) = pklurxraca vozudxkjhi (vvhsqwdcuz, mjqhvjcyvo - dxckfppuuc)
-
06 Mar 2019
(Experimental: MEDI2070 700mg)
uikrvgeugv(nkowablnuw) = fdaejwgrcc vozudxkjhi (vvhsqwdcuz, gkoyxwagmb - hpzyrymkvb)
Not Applicable
-
-
gdvdbopgct(hjcouvwmct) = 16.3% qrktqsbztl (ofrflyzrde )
-
01 Oct 2018
Phase 2
119
(pmdxkqajfx) = ztuaieemqj fkearevyav (msryihkvsk )
Positive
01 Jul 2017
Placebo
(pmdxkqajfx) = hmdjarxjjy fkearevyav (msryihkvsk )
Phase 2
Crohn Disease
C-reactive protein
121
weofpyqtbz(fcthvmkzbs) = imnbwvuhfz oqktbihmqd (bujxkybmsi )
Positive
19 Jan 2015
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Regulation

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