[Translation] Safety, tolerability, pharmacokinetics, and pharmacodynamics of a single dose of HRS-5817 injection in healthy or obese subjects: a randomized, double-blind, placebo-controlled, dose-escalation phase 1 study
主要目的:评价HRS-5817单次皮下注射给药的安全性和耐受性。
次要目的:评价HRS-5817单次皮下注射给药的药代动力学(PK)特征;评价HRS-5817单次皮下注射给药的药效学(PD)特征;评价HRS-5817单次皮下注射给药的免疫原性特征。
[Translation] Primary objective: To evaluate the safety and tolerability of a single subcutaneous injection of HRS-5817.
Secondary objectives: To evaluate the pharmacokinetic (PK) characteristics of a single subcutaneous injection of HRS-5817; To evaluate the pharmacodynamic (PD) characteristics of a single subcutaneous injection of HRS-5817; To evaluate the immunogenicity characteristics of a single subcutaneous injection of HRS-5817.