Last update 25 Oct 2025

IRE1alpha inhibitors (OptiKira)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
IRE1
Action
inhibitors
Mechanism
IRE1 inhibitors(Serine/threonine-protein kinase/endoribonuclease IRE1 inhibitors)
Therapeutic Areas
Congenital DisordersEndocrinology and Metabolic DiseaseEye Diseases+ [5]
Active Indication
Diabetes MellitusIdiopathic Pulmonary FibrosisRetinitis Pigmentosa+ [3]
Inactive Indication-
Originator Organization
Optikira LLCOptikira LLC
Active Organization
Optikira LLCOptikira LLC
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with IRE1alpha inhibitors (OptiKira)
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100 Translational Medicine associated with IRE1alpha inhibitors (OptiKira)
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100 Patents (Medical) associated with IRE1alpha inhibitors (OptiKira)
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100 Deals associated with IRE1alpha inhibitors (OptiKira)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes MellitusPreclinical
United States
Optikira LLCOptikira LLC
-
Idiopathic Pulmonary FibrosisPreclinical
United States
Optikira LLCOptikira LLC
-
Retinitis PigmentosaPreclinical
United States
Optikira LLCOptikira LLC
-
Metabolic Dysfunction Associated SteatohepatitisDiscovery
United States
Optikira LLCOptikira LLC
-
Motor Neuron DiseaseDiscovery
United States
Optikira LLCOptikira LLC
-
NeoplasmsDiscovery
United States
Optikira LLCOptikira LLC
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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