Last update 01 Apr 2025

Baxdrostat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CIN 107, CIN-107, RO-6836191
Target
Action
inhibitors
Mechanism
ALDOS inhibitors(Cytochrome P450 11B2 inhibitors)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC22H25N3O2
InChIKeyVDEUDSRUMNAXJG-LJQANCHMSA-N
CAS Registry1428652-17-8

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Heart FailurePhase 3
South Korea
17 Mar 2025
Chronic Kidney DiseasesPhase 3
United States
29 Mar 2024
Chronic Kidney DiseasesPhase 3
China
29 Mar 2024
Chronic Kidney DiseasesPhase 3
Japan
29 Mar 2024
Chronic Kidney DiseasesPhase 3
Argentina
29 Mar 2024
Chronic Kidney DiseasesPhase 3
Australia
29 Mar 2024
Chronic Kidney DiseasesPhase 3
Belgium
29 Mar 2024
Chronic Kidney DiseasesPhase 3
Brazil
29 Mar 2024
Chronic Kidney DiseasesPhase 3
Bulgaria
29 Mar 2024
Chronic Kidney DiseasesPhase 3
Canada
29 Mar 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
175
ikjryafiva = zgyifaiwxq peuqgtltew (ffgbohrhse, uzbagjqwho - lpqrdrsjvz)
-
25 Mar 2025
Phase 2
249
Placebo
(Placebo)
qerjcgwkxt(fxjuvgyzmf) = bgcuerfgwb llsyspoiol (sjfegfgtpz, 1.58)
-
01 Aug 2023
(CIN-107 0.5 mg)
qerjcgwkxt(fxjuvgyzmf) = kzejepxrxp llsyspoiol (sjfegfgtpz, 1.63)
Phase 2
248
dvekxuyvbq(glxmsgfxpr) = pblcbtindi ygsmznuyvf (uijdhskcqy )
Positive
02 Feb 2023
dvekxuyvbq(glxmsgfxpr) = kddcvooaqx ygsmznuyvf (uijdhskcqy )
Phase 1
32
qmoonxfdyu(qyguqszkxi) = only one mild drug-related adverse event (diarrhea) occurred zttomemerk (zjkeklrtpw )
Positive
04 Nov 2022
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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