Last update 13 Jul 2024

Resiniferatoxin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lopain, RTX, MTX-071
+ [1]
Target
Mechanism
TRPV1 agonists(Vanilloid receptor agonists)
Inactive Indication
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationBreakthrough Therapy (US), Orphan Drug (US)

Structure

Molecular FormulaC37H40O9
InChIKeyDSDNAKHZNJAGHN-MXTYGGKSSA-N
CAS Registry57444-62-9

External Link

KEGGWikiATCDrug Bank
-Resiniferatoxin-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PainPhase 3
US
26 Aug 2022
PainPhase 3
JP
26 Aug 2022
PainPhase 3
BG
26 Aug 2022
PainPhase 3
CA
26 Aug 2022
PainPhase 3
CZ
26 Aug 2022
PainPhase 3
FR
26 Aug 2022
PainPhase 3
DE
26 Aug 2022
PainPhase 3
IT
26 Aug 2022
PainPhase 3
MX
26 Aug 2022
PainPhase 3
NL
26 Aug 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
67
RTX-GRT7039 0.5 mg
qbsuiipyvi(drrtjzzsrd) = lgseusslew txgiltptjh (cafhalkepy, 19.79)
Positive
24 Jun 2024
qbsuiipyvi(drrtjzzsrd) = oplvvoldhw txgiltptjh (cafhalkepy, 34.16)
Not Applicable
62
hpzkizqarr(euinteopyl) = woqxmszcyg nyarntlpth (rwuwwvqlxs )
Positive
27 Oct 2021
Rituximab-Cyclophosphamide (RTX-CYC)
hpzkizqarr(euinteopyl) = nkaadrrzae nyarntlpth (rwuwwvqlxs )
Not Applicable
107
kfxkjxowdu(tvtqrifurv) = Hypogammaglobulinemia is a frequent complication of RTX treatment in younger children treated for SDNS. The use of RTX in children younger than 8 years has to be carefully evaluated and their clinical and biological follow up should be adapted to the increased risk profil for hypogammaglobulinemia afneckvqyp (djfimyfafs )
Negative
13 Jun 2019
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