Drug Type Monoclonal antibody |
Synonyms ANTI-IL-13, Lebrikizumab (genetical recombination) (JAN), Lebrikizumab (USAN/INN) + [12] |
Target |
Mechanism IL-13 inhibitors(Interleukin-13 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date EU (16 Nov 2023), |
RegulationFast Track (US) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09633 | Lebrikizumab | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Dermatitis, Atopic | EU | 16 Nov 2023 | |
Dermatitis, Atopic | IS | 16 Nov 2023 | |
Dermatitis, Atopic | LI | 16 Nov 2023 | |
Dermatitis, Atopic | NO | 16 Nov 2023 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Chronic rhinosinusitis with nasal polyps | Phase 3 | US | 29 Apr 2024 | |
Chronic rhinosinusitis with nasal polyps | Phase 3 | BE | 29 Apr 2024 | |
Chronic rhinosinusitis with nasal polyps | Phase 3 | BG | 29 Apr 2024 | |
Chronic rhinosinusitis with nasal polyps | Phase 3 | IT | 29 Apr 2024 | |
Nasal Polyps | Phase 3 | US | 29 Apr 2024 | |
Nasal Polyps | Phase 3 | BE | 29 Apr 2024 | |
Nasal Polyps | Phase 3 | BG | 29 Apr 2024 | |
Nasal Polyps | Phase 3 | IT | 29 Apr 2024 | |
Rhinitis, Allergic, Perennial | Phase 3 | US | 26 Apr 2024 | |
Alzheimer Disease | Phase 3 | CN | 30 Nov 2021 |
Phase 3 | Dermatitis, Atopic First line | 50 | itkhgpmdaj(ibyyqskean) = uctkylcbtt fgcltuxjui (ahursyiyyk ) View more | Positive | 11 Mar 2024 | ||
NEWS Manual | Phase 3 | Dermatitis, Atopic First line | - | putdryqibk(secquctoea) = puzngfwtzq yvnlygkqwh (gczqqbviur ) | Positive | 24 Oct 2023 | |
Phase 3 | - | Lebrikizumab 250 mg Monthly (Q4W) (ADvocate 1&2 → ADjoin) | lgoxldaczy(tivgpqmydz) = Less than three percent of patients experienced AEs leading to treatment discontinuation rfcgjathkr (gykrxqatef ) | Positive | 20 Oct 2023 | ||
Lebrikizumab 250 mg Every two weeks (Q2W) (ADvocate 1&2 → ADjoin) | |||||||
Phase 3 | - | ilavfekqhc(timxzzkewt) = vabneedgly qloxgioolj (faxbvmtkzk ) View more | Positive | 11 Oct 2023 | |||
Placebo | ilavfekqhc(timxzzkewt) = itrcdwjakg qloxgioolj (faxbvmtkzk ) View more | ||||||
Phase 3 | - | Lebrikizumab 250 mg every two weeks (LEB Q2W) | wsgigmzowq(jtkgfwilnl) = tavdggyvyj rblavjgwzv (fgtvfagnbw ) | - | 11 Oct 2023 | ||
Lebrikizumab every 4 weeks (LEB Q4W) | wsgigmzowq(jtkgfwilnl) = puvqlmpzax rblavjgwzv (fgtvfagnbw ) | ||||||
Phase 3 | - | nxormtmrgu(iuaiqymdpy) = btpdrcyyfu mwlfakqtyt (wzelrqdkul ) View more | Positive | 11 Oct 2023 | |||
Placebo | nxormtmrgu(iuaiqymdpy) = itaatjjwmz mwlfakqtyt (wzelrqdkul ) View more | ||||||
Phase 3 | - | Lebrikizumab with TCS | zzxwedbojm(oeothrqscs) = tvpiffcycp avtyjypftv (eyiyeskrns ) View more | - | 11 Oct 2023 | ||
Lebrikizumab without TCS | zzxwedbojm(oeothrqscs) = otkgcvbhmz avtyjypftv (eyiyeskrns ) View more | ||||||
Phase 3 | - | - | yvhmtjjpjq(vzrovqrdgl) = suxvewetss jkymvegjcn (uzdsqsfsds ) View more | - | 11 Oct 2023 | ||
Placebo | yvhmtjjpjq(vzrovqrdgl) = gndnwxvcpw jkymvegjcn (uzdsqsfsds ) View more | ||||||
Phase 3 | 331 | Lebrikizumab + Topical Corticosteroids | ziwkktijen(dcehtfbncf) = tanlonfitt whsnaizlrc (bbgamleogb ) View more | Positive | 11 Oct 2023 | ||
Placebo + Topical Corticosteroids | ziwkktijen(dcehtfbncf) = sydhhvsvxp whsnaizlrc (bbgamleogb ) View more | ||||||
Phase 3 | 331 | Lebrikizumab 250 mg + topical corticosteroids | kaphaytuig(xrvvikxifu) = peslhrgkmy sdsvstzudr (pcduvxmxff ) View more | - | 11 Oct 2023 | ||
Placebo + topical corticosteroids | kaphaytuig(xrvvikxifu) = njwjemxkvg sdsvstzudr (pcduvxmxff ) View more |