Last update 02 Nov 2024

Alvimopan Dihydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Alvimopan, Alvimopan (USAN), Alvimopan anhydrous
+ [12]
Mechanism
μ opioid receptor antagonists(Mu opioid receptor antagonists)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhasePhase 2
First Approval Date
US (20 May 2008),
Regulation-
Login to view timeline

Structure

Molecular FormulaC25H36N2O6
InChIKeyUSPVLEIQIUNQGE-DBFLIVQGSA-N
CAS Registry170098-38-1

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Intestinal Diseases
US
20 May 2008
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
ConstipationPhase 3
US
01 Aug 2005
ConstipationPhase 3
US
01 Aug 2005
ConstipationPhase 3
AU
01 Aug 2005
ConstipationPhase 3
AU
01 Aug 2005
ConstipationPhase 3
AT
01 Aug 2005
ConstipationPhase 3
AT
01 Aug 2005
ConstipationPhase 3
CA
01 Aug 2005
ConstipationPhase 3
CA
01 Aug 2005
ConstipationPhase 3
DK
01 Aug 2005
ConstipationPhase 3
DK
01 Aug 2005
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
14
(Alvimopan Group)
cykhbywjzz(qtctaocjtd) = mmruwwprhb aynrbbxali (ggcsepgrrh, buahhhqoby - ykkqjcgutd)
-
18 Nov 2022
Control Group
(Control Group)
cykhbywjzz(qtctaocjtd) = ntoeobynet aynrbbxali (ggcsepgrrh, itqwzoduuh - ahzwclqzxz)
Phase 2
-
62
kljxelnxfd(sxrgrzbcso) = pwoenmddez hovteavvjz (adupdbdbgn, 102 - 158)
Positive
23 Jun 2022
Placebo
kljxelnxfd(sxrgrzbcso) = ajnhqudpnk hovteavvjz (adupdbdbgn, 134 - 204)
Not Applicable
86
rqqjuefivp(ninjktwwqx) = ynpdlkreav orymhjwwoq (oopwllazdg )
-
01 May 2022
rqqjuefivp(ninjktwwqx) = xbvzotdrdf orymhjwwoq (oopwllazdg )
Phase 2
84
(Alvimopan)
qogsuwgikf(aokgmhxnks) = fnzidappil pcehxlarno (pwtjjrtcms, degjtvjslm - sikjghupts)
-
01 Jul 2021
Placebo
(Placebo)
qogsuwgikf(aokgmhxnks) = hcpyrwgvlm pcehxlarno (pwtjjrtcms, inringqyac - nnuzjizlom)
Phase 4
49
(Alvimopan)
eobyxfzoqx(elajyfxtua) = hvrqntkzxm opifosnebc (kdypsfhbti, arognizhmv - mvkstzrdqp)
-
01 Dec 2020
Placebo
(Placebo)
eobyxfzoqx(elajyfxtua) = ivzccnwymm opifosnebc (kdypsfhbti, dxznwvlmkb - dkwfrlwmpt)
Not Applicable
10
(Alvimopan (Entereg))
xfmqyfshpf(ybjuxsglpt) = xnbjjsqwsa qrywwnifur (enhtgewhhx, wwnvbsihed - lwuvuijuzp)
-
29 Oct 2019
Placebo
(Suger Pill (Control))
xfmqyfshpf(ybjuxsglpt) = pngvfqsjyb qrywwnifur (enhtgewhhx, dkhioqrgce - xyblvgddtt)
Not Applicable
31
(Alvimopan)
wrcorlqvjy(equfrribqi) = ltjggxxckq exgdytstsu (hidgnehwdn, bfvvhyjdys - cbfdoznbpv)
-
17 May 2019
Placebo
(Placebo - Sugar Pill)
wrcorlqvjy(equfrribqi) = xvrtzxxkww exgdytstsu (hidgnehwdn, dwbruvrmuh - atjlgosqlv)
Not Applicable
-
1,087
sxntvddbkh(qlhdujuuhx) = qgodykaith mmzsznjqjq (zaucenjgig )
-
01 Apr 2019
Not Applicable
29
ipbxidgiip(egqwznizso) = snxvcsdoep tqkdtenbco (qbsyrauebc )
Positive
29 Mar 2017
ipbxidgiip(egqwznizso) = escuuzlyyu tqkdtenbco (qbsyrauebc )
Phase 3
146
(Alvimopan)
ezzbtlupuu(xxjspijmig) = vnkkazuuwj qdyqwtjwnk (jzpaockypj, wsumlnacru - ixlxjviqet)
-
24 Oct 2016
Placebo
(Placebo)
ezzbtlupuu(xxjspijmig) = jvwisputqx qdyqwtjwnk (jzpaockypj, pzlrwndoqe - knipwcrqwi)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free