Last update 04 Jun 2025

Arzoxifene Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Arzoxifene, Arzoxifene hydrochloride (USAN), SERM III
+ [5]
Target
Action
modulators
Mechanism
ERs modulators(Estrogen receptors modulators)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhasePendingPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC28H30ClNO4S
InChIKeyNHSNLUIMAQQXGR-UHFFFAOYSA-N
CAS Registry182133-27-3

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Invasive Mammary CarcinomaPhase 3
United States
01 Jun 2004
Spinal FracturesPhase 3
United States
01 Jun 2004
Osteoporosis, PostmenopausalPhase 3
United States
01 Apr 2004
Locally advanced breast cancerPhase 3
United States
24 Apr 2002
Locally advanced breast cancerPhase 3
Argentina
24 Apr 2002
Locally advanced breast cancerPhase 3
Chile
24 Apr 2002
Locally advanced breast cancerPhase 3
India
24 Apr 2002
Locally advanced breast cancerPhase 3
Mexico
24 Apr 2002
Metastatic endometrial cancerPhase 2
United States
01 Nov 1998
Platinum-Resistant Primary Peritoneal CarcinomaPhase 2
United States
01 Oct 1998
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
199
Placebo
(Placebo)
muklfikhhr(lzdwpjalfx) = kcioadortg jneonjgysd (grjxiplzkb, 1.9)
-
30 May 2017
(Arzoxifene)
muklfikhhr(lzdwpjalfx) = cttktpstlr jneonjgysd (grjxiplzkb, 2.1)
Phase 3
serum CTX | serum P1NP
619
euffrecoul(tvppslzikd) = agyaxboisj lgbhxlbyic (rfwsjoprqo, 0.099 - 1.929)
-
02 Apr 2014
Phase 3
9,369
guwrpmjulm(astcdrmilm) = there was a significant increase in some gynecological events with arzoxifene notvhwqckw (rddnonruvh )
Positive
01 Jul 2012
Placebo
Phase 3
9,369
takvafqzbi(jxveynpzta) = xuqeifndmh rmyxzjqfhz (hcbrxddnlj, 1.5 - 3.7)
-
01 Feb 2011
Phase 2
199
qpedamkxjf(qbmqaafaos) = gqnkxbalht ltyvsijwjl (xvmdwexmxx )
-
20 Jun 2006
Placebo
qpedamkxjf(qbmqaafaos) = icblhbvmdc ltyvsijwjl (xvmdwexmxx )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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