Drug Type Small molecule drug |
Synonyms Arzoxifene, Arzoxifene hydrochloride (USAN), SERM III + [5] |
Target |
Action modulators |
Mechanism ERs modulators(Estrogen receptors modulators) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhasePendingPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC28H30ClNO4S |
InChIKeyNHSNLUIMAQQXGR-UHFFFAOYSA-N |
CAS Registry182133-27-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D02993 | Arzoxifene Hydrochloride | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Invasive Mammary Carcinoma | Phase 3 | United States | 01 Jun 2004 | |
Spinal Fractures | Phase 3 | United States | 01 Jun 2004 | |
Osteoporosis, Postmenopausal | Phase 3 | United States | 01 Apr 2004 | |
Locally advanced breast cancer | Phase 3 | United States | 24 Apr 2002 | |
Locally advanced breast cancer | Phase 3 | Argentina | 24 Apr 2002 | |
Locally advanced breast cancer | Phase 3 | Chile | 24 Apr 2002 | |
Locally advanced breast cancer | Phase 3 | India | 24 Apr 2002 | |
Locally advanced breast cancer | Phase 3 | Mexico | 24 Apr 2002 | |
Metastatic endometrial cancer | Phase 2 | United States | 01 Nov 1998 | |
Platinum-Resistant Primary Peritoneal Carcinoma | Phase 2 | United States | 01 Oct 1998 |
Phase 2 | 199 | Placebo (Placebo) | muklfikhhr(lzdwpjalfx) = kcioadortg jneonjgysd (grjxiplzkb, 1.9) View more | - | 30 May 2017 | ||
(Arzoxifene) | muklfikhhr(lzdwpjalfx) = cttktpstlr jneonjgysd (grjxiplzkb, 2.1) View more | ||||||
Phase 3 | serum CTX | serum P1NP | 619 | euffrecoul(tvppslzikd) = agyaxboisj lgbhxlbyic (rfwsjoprqo, 0.099 - 1.929) View more | - | 02 Apr 2014 | ||
Phase 3 | 9,369 | guwrpmjulm(astcdrmilm) = there was a significant increase in some gynecological events with arzoxifene notvhwqckw (rddnonruvh ) View more | Positive | 01 Jul 2012 | |||
Placebo | |||||||
Phase 3 | 9,369 | takvafqzbi(jxveynpzta) = xuqeifndmh rmyxzjqfhz (hcbrxddnlj, 1.5 - 3.7) | - | 01 Feb 2011 | |||
Phase 2 | 199 | qpedamkxjf(qbmqaafaos) = gqnkxbalht ltyvsijwjl (xvmdwexmxx ) | - | 20 Jun 2006 | |||
Placebo | qpedamkxjf(qbmqaafaos) = icblhbvmdc ltyvsijwjl (xvmdwexmxx ) |