Last update 20 Mar 2025

SYS-6002

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
重组人源化抗人Nectin4单克隆抗体-MMAE偶联药物(石药巨石)
+ [1]
Target
Action
inhibitors
Mechanism
nectin-4 inhibitors(Nectin-4 inhibitors)
Therapeutic Areas
Inactive Indication-
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (United States)
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Structure/Sequence

Molecular FormulaC39H67N5O7
InChIKeyDASWEROEPLKSEI-UIJRFTGLSA-N
CAS Registry474645-27-7
View All Structures (2)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
United Kingdom
01 Apr 2024
Advanced Malignant Solid NeoplasmPhase 2
Turkey
01 Apr 2024
Advanced Malignant Solid NeoplasmPhase 2
Romania
01 Apr 2024
Advanced Malignant Solid NeoplasmPhase 2
United States
01 Apr 2024
Advanced Malignant Solid NeoplasmPhase 2
Spain
01 Apr 2024
Advanced Malignant Solid NeoplasmPhase 2
France
01 Apr 2024
Advanced Malignant Solid NeoplasmPhase 2
Italy
01 Apr 2024
Nectin-4 positive Advanced Malignant Solid TumorPhase 2
France
01 Apr 2024
Nectin-4 positive Advanced Malignant Solid TumorPhase 2
Italy
01 Apr 2024
Nectin-4 positive Advanced Malignant Solid TumorPhase 2
Romania
01 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
31
(ctjwuorwyq) = none qcbvpesfhq (srjzlwhovu )
Positive
11 Feb 2025
Phase 1
37
CRB-701 (SYS6002)
(mUC)
(dwxdgdcuxh) = hjklsbrdmm dqrxwwjacz (iztfnkibcw )
Positive
07 Nov 2024
CRB-701 (SYS6002)
(cervical cancer)
(dwxdgdcuxh) = yamejelwdd dqrxwwjacz (iztfnkibcw )
Phase 1
Solid tumor
Last line
-
(ymkvlqyhdw) = None rrvgtvuvqu (dxdldklvoy )
Positive
24 May 2024
Phase 1
18
(mzfgdjhglj) = not observed gglpmvtbef (vjdraargpa )
Positive
26 Jan 2024
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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