Drug Type Bispecific T-cell Engager (BiTE) |
Synonyms Anti-CD3 X anti-HER-2/neu, Rexomab, Rexomun |
Target |
Action stimulants, antagonists |
Mechanism CD3 stimulants(T cell surface glycoprotein CD3 stimulants), HER2 antagonists(Receptor tyrosine-protein kinase erbB-2 antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Ertumaxomab | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Breast Cancer | Phase 2 | Germany | 07 Nov 2014 | |
Advanced breast cancer | Phase 2 | Belgium | 01 Jul 2006 | |
Metastatic breast cancer | Phase 2 | Belgium | 01 Jul 2006 |
Phase 1 | 17 | (Anti-CD3 activated T cells (ATC) armed with Her2Bi) | qjxqjqguhb(zjutxxiovm) = vvrtxzzfcf qxnhcczntf (umynbrjlbc ) | - | 20 May 2008 |