Last update 24 Mar 2025

Reltecimod

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Reltecimod (USAN/INN), Reltecimod Sodium, AB-103
+ [1]
Action
inhibitors
Mechanism
CD28 inhibitors(T-cell-specific surface glycoprotein CD28 inhibitors), PLK1 inhibitors(Polo like kinase 1 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC46H72N10O15S
InChIKeyVRNHFZYMPDKTBS-WYUJEMNCSA-N
CAS Registry1447799-33-8

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute kidney injury due to sepsisPhase 3
United States
24 May 2018
Acute kidney injury due to sepsisPhase 3
France
24 May 2018
PeritonitisPhase 3
United States
24 May 2018
PeritonitisPhase 3
France
24 May 2018
Fasciitis, NecrotizingPhase 3
United States
01 Dec 2015
Fasciitis, NecrotizingPhase 3
France
01 Dec 2015
Fournier GangrenePhase 3
United States
01 Dec 2015
Fournier GangrenePhase 3
France
01 Dec 2015
Soft Tissue InfectionsPhase 3
United States
01 Dec 2015
Soft Tissue InfectionsPhase 3
France
01 Dec 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
43
(AB103 0.25 mg/kg)
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-
18 Aug 2021
(AB103 0.5 mg/kg)
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Phase 1
-
25
(AB103 7.5 µg/kg)
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-
27 Apr 2021
(AB103 37.5 µg/kg)
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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