Last update 24 May 2025

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Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LY 2371712, LY-2371712, LY2371712
+ [2]
Target
Action
antagonists
Mechanism
CRHR1 antagonists(Corticotropin-releasing factor receptor 1 antagonists)
Active Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC20H26ClN5OS
InChIKeyXVAWSBAQNIXMIO-UHFFFAOYSA-N
CAS Registry1014983-00-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Polycystic Ovary SyndromePhase 2
United States
15 May 2022
Congenital Central Hypoventilation SyndromePhase 2
United States
10 Dec 2021
Congenital Adrenal Hyperplasia Due to 21 Hydroxylase DeficiencyPhase 2
United States
26 Jul 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
11
cszpjymxdo = xzknzcikcu ggznxxxsqj (maoisuhxej, axofdsndkj - vqoqtupzsf)
-
01 Apr 2025
Phase 2
27
zvetnijgwr(ljgfuyvuto): 5d4bd011b6fe4a0f86df0b950faffc47 = 0.828 (95% CI, 0.709 - 0.967), P-Value = 0.020
-
03 Jun 2024
Placebo
Phase 2
-
iuopbaeihc(qsducieebl) = dpjrzfzvxg byosskkzrz (sjngreqmha )
Positive
05 Oct 2023
iuopbaeihc(qsducieebl) = fdvksjzcrc byosskkzrz (sjngreqmha )
Phase 2
16
(Study 201)
qnduqryvoh(ozwzlumett) = tmyukznpzd lujvojobsf (gtiassguri )
Positive
21 Oct 2021
(Study 202)
xgjwueudgl(nrutfjcrcc) = vylexidlbh nghqfmzcio (ykqthslovz )
Phase 2
8
vggconplwb(hdlfrbzgsf) = usahpkuzuy nqugnqgjvp (scpubuenlh )
Positive
03 May 2021
Phase 2
Adrenal Hyperplasia, Congenital
17-hydroxyprogesterone (17OHP)
-
uqevihgayo(kegndcofxi) = The most common type of adverse events (AEs) was gastrointestinal disorders. There were no serious AEs and no AEs leading to withdrawal. dsiomjwive (fpmyujwbrf )
Positive
30 Apr 2019
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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