Maqianzi Zongjian Nangpao Gel

(1) Conduct human tolerance test of strychnine alkaloids vesicle gel on healthy adult subjects to determine the human tolerance dose range and safety; (2) Conduct pharmacokinetic test at the same time as tolerance test to detect the blood concentration of strychnine and strychnine, components of strychnine vesicle gel, estimate pharmacokinetic parameters, and evaluate its pharmacokinetic characteristics; (3) Provide experimental basis for the formulation of late clinical trial plan of strychnine vesicle gel.