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Last update 31 Jul 2025
Nelmastobart
Last update 31 Jul 2025
Overview
Basic Info
Drug Type Monoclonal antibody |
Synonyms Anti STT-003 Ab, Anti-butyrophilin 1A1 mAb(STCube/MD Anderson Cancer Center), HSTC 810 + [2] |
Target |
Action inhibitors |
Mechanism BTN1A1 inhibitors(butyrophilin subfamily 1 member A1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 776944511H
Source: *****
Sequence Code 776944512L
Source: *****
Related
3
Clinical Trials associated with NelmastobartNCT06873763
A Single-arm, Phase Ib/2 Study of Nelmastobart in Combination With Trifluridine/Tipiracil and Bevacizumab in Metastatic/Recurrent Colorectal Cancer Patients With Resistance or Intolerance to Oxaliplatin and Irinotecan-based Chemotherapy
NCT06016270
A Phase Ib/II Study of hSTC810 in Combination With Paclitaxel in Relapsed or Refractory Extensive Stage Small Cell Lung Cancer
NCT05231746
A Phase 1, Multicenter, Open-label Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of hSTC810 Monotherapy in Subjects With Advanced Solid Tumors
100 Clinical Results associated with Nelmastobart
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100 Translational Medicine associated with Nelmastobart
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100 Patents (Medical) associated with Nelmastobart
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100 Deals associated with Nelmastobart
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Metastatic Colorectal Carcinoma | Phase 2 | South Korea | 09 Jun 2025 | |
| Extensive stage Small Cell Lung Cancer | Phase 2 | United States | 13 Feb 2024 | |
| Head and Neck Neoplasms | Phase 2 | South Korea | - | |
| Head and Neck Neoplasms | Phase 2 | - | - | |
| Lung Cancer | Phase 2 | South Korea | - | |
| Advanced Malignant Solid Neoplasm | Phase 1 | United States | 18 Apr 2022 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Phase 1 | Colonic Cancer BTN1A1 | YAP1 | - | fwehghcqkr(mhyretayha) = Treatment with hSTC810 demonstrated a favorable safety profile, with the most common adverse events being low-grade fatigue and infusion-related reactions rwdvladnyv (alvvqgkvoi ) View more | Positive | 30 Apr 2025 | ||
Phase 1 | Colonic Cancer BTN1A1 | 47 | (all cohorts) | bzbbmjvegr(bfcvzitlgb) = flhxvfegqt cianqzyjct (iegrvpndxl ) View more | Positive | 23 Jan 2025 | |
bzbbmjvegr(bfcvzitlgb) = xsxheznaep cianqzyjct (iegrvpndxl ) View more | |||||||
Phase 1 | 12 | ejzkaxfcte(zwyvvwklof) = ehsxivtdqj lxhfaecnom (vyzaisclkz ) | Positive | 23 Jan 2025 | |||
Phase 1 | Advanced Malignant Solid Neoplasm BTN1A1 | PD-L1 | 47 | xxjjtlaeko(ratpvnobgp) = showed a linear PK and consistent exposure ygybjqbkan (ofdgcjntwy ) | Positive | 05 Nov 2024 | ||
Phase 1 | 39 | STC810 | ylvdsbuamp(mreeewtmqs) = dnktxvnqlk ddarnnagtx (jtdbzppqnu ) View more | Positive | 26 May 2023 |
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Translational Medicine
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Core Patent
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Biosimilar
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Regulation
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