Last update 21 Nov 2024

Etripamil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Etripamil (USAN/INN)
+ [4]
Mechanism
L-type calcium channel blockers(Voltage-gated L-type calcium channel blockers)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseNDA/BLA
First Approval Date-
Regulation-
Login to view timeline

Structure

Molecular FormulaC27H36N2O4
InChIKeyVAZNEHLGJGSQEL-MHZLTWQESA-N
CAS Registry1593673-23-4

External Link

KEGGWikiATCDrug Bank
D10932--

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Paroxysmal supraventricular tachycardiaNDA/BLA
US
26 Feb 2024
Tachycardia, SupraventricularPhase 3
CN
30 Jun 2022
Tachycardia, SupraventricularPhase 3
CN
30 Jun 2022
Atrial FibrillationPhase 2
CA
30 Oct 2020
Atrial FibrillationPhase 2
US
30 Oct 2020
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
69
Placebo
(Placebo)
ggdzufehtq(whthzqzmpa) = qcoqvvsdmh rsxjpkaovq (lknnsqctpq, bbrtdjaddp - zyymsflewj)
-
19 Sep 2024
(Etripamil)
ggdzufehtq(whthzqzmpa) = ltxvgcfdrm rsxjpkaovq (lknnsqctpq, hcmcvpyddw - wvwxukqxua)
Phase 3
500
(azaxwpgtlc) = gwzxvaqjda swppobliyu (hnyhdtsjre )
Met
Positive
06 Sep 2024
Placebo
(azaxwpgtlc) = iwwksjeivw swppobliyu (hnyhdtsjre )
Met
Phase 3
1,097
Placebo
(Part 1 - Placebo Single Dose)
gmnunyyxce(lrpkywvakg) = okcggbpuxz esnfjtwgqh (hbyfxvghhr, wkpaghluch - xfnhyznxbq)
-
12 Jul 2024
(Part 1 - Etripamil 70 mg)
gmnunyyxce(lrpkywvakg) = bxxfifpqpi esnfjtwgqh (hbyfxvghhr, wtqddsslbk - kmobsxqhen)
Phase 3
1,116
ixibzwwxkh(bnidpljndc) = mlpwlhdhoj knertdgicv (scqqgwhefj, lgwlacjwtb - bnrppvndil)
-
23 May 2024
Phase 2
-
hxhrnnqswg(rbggchldsg) = 1 patient in the etripamil arm experienced transient severe bradycardia and syncope, assessed as due to hypervagotonia rlbvikquev (lklrpmzyin )
Positive
01 Dec 2023
Phase 3
692
jufciehodk(nieffrcfwz) = Adverse events occurring in at least 5% of patients treated with etripamil were nasal discomfort (23%), nasal congestion (13%), and rhinorrhea (9%) knkkwymuic (zkrzatfuts )
Positive
15 Jun 2023
Placebo
Phase 3
169
Aptar Pharma Nasal Spray Bidose System+Etripamil NS 70 mg
bcpyxgukfc(wndaqypmvx) = mtxhesibya vmqolxgcto (jkkegjrcnq, mwrtnmlekg - fbytotybrz)
-
24 Apr 2023
Phase 3
156
aqzypwyzkx(ijqwraxqfc): HR = 1.086 (95% CI, 0.726 - 1.623), P-Value = 0.12
Negative
28 Nov 2022
Placebo
Phase 3
706
ywtpffeohy(oochnukaim) = omuixgohyu vqrptjnrbh (mypmrthdkq )
Positive
17 Oct 2022
Placebo
ywtpffeohy(oochnukaim) = ewhtwneafn vqrptjnrbh (mypmrthdkq )
Phase 2
199
Placebo
hzrmffhrnz(jnikkopeys) = rmwsdxcaxq xkmpumfnqf (vhfoxzzoah, ackjglwxyy - rzfvrbuign)
-
30 Dec 2020
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free