Last update 01 Nov 2024

MEN-1611

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Izorlisib
+ [1]
Mechanism
Phosphatidylinositol 3-kinase family inhibitors
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC15H19N7O3S
InChIKeyJEGHXKRHKHPBJD-UHFFFAOYSA-N
CAS Registry1007207-67-1

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 2
IT
20 Jul 2020
Metastatic Colorectal CarcinomaPhase 2
ES
20 Jul 2020
Metastatic Colorectal CarcinomaPhase 2
US
20 Jul 2020
Metastatic Colorectal CarcinomaPhase 2
FR
20 Jul 2020
Colorectal CancerPhase 1
DE
20 Jul 2020
Colorectal CancerPhase 1
NL
20 Jul 2020
Colorectal CancerPhase 1
US
20 Jul 2020
Colorectal CancerPhase 1
FR
20 Jul 2020
Colorectal CancerPhase 1
ES
20 Jul 2020
Colorectal CancerPhase 1
PL
20 Jul 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
PIK3CA mutated/HER2 Positive Breast Cancer
HER2 Positive | PIK3CA Mutation
36
MEN1611+trastuzumab
(dgqjkoirve) = Serious TRAEs were experienced by 8 pts (19%): hyperglycemia 3 pts, diarrhea 2 pts, general physical health deterioration, generalized edema, and pneumonitis (1 pt each). nzrghyqsqc (nnxbtxgxbi )
Positive
16 Sep 2021
MEN1611+trastuzumab+fulvestrant
Phase 1
62
oeiavrdlfg(euphbkwndq) = usmycbyvkl lowqmmqkfn (hcxvktonff )
-
01 Jul 2021
oeiavrdlfg(euphbkwndq) = eongkptorf lowqmmqkfn (hcxvktonff )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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