Last update 01 Nov 2024

VSV-IFNbeta-NIS

Overview

Basic Info

Drug Type
Oncolytic virus
Synonyms
VSV-IFNβ-NIS
Mechanism
IFNβ stimulants(Interferon beta stimulants), NIS stimulants(solute carrier family 5 member 5 stimulants), Cell death stimulants
+ [1]
Inactive Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerPhase 2
BR
24 Apr 2020
Colorectal CancerPhase 2
US
24 Apr 2020
MelanomaPhase 2
BR
24 Apr 2020
MelanomaPhase 2
US
24 Apr 2020
Squamous Cell Carcinoma of Head and NeckPhase 2
US
24 Apr 2020
Squamous Cell Carcinoma of Head and NeckPhase 2
BR
24 Apr 2020
Neuroendocrine CarcinomaPhase 2
US
09 Apr 2019
Non-Small Cell Lung CancerPhase 2
US
09 Apr 2019
Malignant Solid NeoplasmDiscovery
US
17 Apr 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
43
(kbqjpcsmac) = Grades 3 and higher AEs were hematologic with transient lymphopenia (63.6%), neutropenia (36.4%) being the most common. porkqgofnc (toobpdmsfc )
Positive
31 May 2023
Phase 1
30
(firrwyulfi) = oommpwfwhw fvucelznzt (mtuigxdtmf )
Positive
31 May 2023
Phase 1
15
(zoncpetzvr) = CRS grades 1 (6.7%) and 2 (46.6%) were the non-hematologic AEs of note. jijbossztd (jurblemylr )
Positive
20 May 2021
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Regulation

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