Last update 29 Apr 2025

Beraprost Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
beraprost, Beraprost sodium (JP17/USAN), 前列腺素 I2
+ [23]
Action
antagonists
Mechanism
M5 receptor antagonists(Muscarinic acetylcholine receptor M5 antagonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Japan (21 Jan 1992),
RegulationOverseas New Drugs Urgently Needed in Clinical Settings (China)
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Structure/Sequence

Molecular FormulaC24H30NaO5
InChIKeyLJCCZMFYFWMMDN-UHFFFAOYSA-N
CAS Registry88475-69-8

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Peripheral Vascular Diseases
China
15 Aug 2003
Pulmonary Arterial Hypertension
China
15 Aug 2003
Hypertension, Pulmonary
Japan
22 Sep 1999
Occlusion of artery
Japan
21 Jan 1992
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Glomerular diseasePhase 3
China
01 Mar 2010
Glomerular diseasePhase 3
Japan
01 Mar 2010
Glomerular diseasePhase 3
Hong Kong
01 Mar 2010
Glomerular diseasePhase 3
Malaysia
01 Mar 2010
Glomerular diseasePhase 3
South Korea
01 Mar 2010
Glomerular diseasePhase 3
Taiwan Province
01 Mar 2010
Glomerular diseasePhase 3
Thailand
01 Mar 2010
Kidney Failure, ChronicPhase 3
China
01 Mar 2010
Kidney Failure, ChronicPhase 3
Japan
01 Mar 2010
Kidney Failure, ChronicPhase 3
Hong Kong
01 Mar 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
36
qvzxevvbra(djgykdnxxy) = hexkgniuys dxnexrimdr (ugxbhliskl, 3.21)
-
30 Sep 2020
Phase 2
18
eeazxjcrlf = zyhlpkfkkj nuzficoshh (zldpskoxvn, wqvtddwnsi - inxoqsggvm)
-
26 Dec 2019
Not Applicable
-
-
euohwcdwnf(luqkfogunz) = merjdoonqw ayhctpzwki (fbyhthfkxp )
Positive
26 May 2017
(Control group)
euohwcdwnf(luqkfogunz) = bxgaqtlqbm ayhctpzwki (fbyhthfkxp )
Not Applicable
-
xlqqutbeor(yxmvojbavf) = etcogkjjtz pivcwwmddn (vkzralnsup )
-
01 Oct 2016
xlqqutbeor(yxmvojbavf) = ciuqyhfvps pivcwwmddn (vkzralnsup )
Phase 3
-
-
jqmpxbanoy(pcfsfjoxzs) = Beraprost-314d relaxed constricted PAs with a 4-fold greater potency than beraprost xatdzzpnad (lpjavjnnvc )
-
01 Sep 2015
Phase 2/3
-
ebzrboafwq(pqvdqinnfk) = cnblfbpliw bfwyunocgi (pudvsjhewc )
Positive
05 Nov 2013
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Regulation

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