Last update 20 Dec 2024

Beraprost Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
beraprost, Beraprost sodium (JP17/USAN), 前列腺素 I2
+ [22]
Mechanism
M5 receptor antagonists(Muscarinic acetylcholine receptor M5 antagonists)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (21 Jan 1992),
RegulationOverseas New Drugs Urgently Needed in Clinical Settings (CN)
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Structure

Molecular FormulaC24H30NaO5
InChIKeyLJCCZMFYFWMMDN-UHFFFAOYSA-N
CAS Registry88475-69-8

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Peripheral Vascular Diseases
CN
15 Aug 2003
Pulmonary Arterial Hypertension
CN
15 Aug 2003
Hypertension, Pulmonary
JP
22 Sep 1999
Occlusion of artery
JP
21 Jan 1992
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Intermittent ClaudicationPhase 2
CN
11 Mar 2023
PainPhase 2
CN
11 Mar 2023
UlcerPhase 2
CN
11 Mar 2023
Renal InsufficiencyPhase 1
JP
01 Aug 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
36
raotidryva(wsdjmvivcb) = ydfzwmdyuq exbicaidoh (poxlrnmjhp, tjeshsxpta - hhbhchielq)
-
30 Sep 2020
Phase 2
18
mszhebjppb(tvdkmhssnj) = dvgvaseuzp inryngtvgs (clonpmview, hdtpxqtvks - ajvofuixbl)
-
26 Dec 2019
Not Applicable
-
-
xcyadqhsxl(okyuftxyhj) = wjlshansbn thxpxpqlic (sdzyvgwkby )
Positive
26 May 2017
(Control group)
xcyadqhsxl(okyuftxyhj) = heqxngevhv thxpxpqlic (sdzyvgwkby )
Not Applicable
-
dnpjrpyvfj(mcwtlxqmkj) = urfcizsgsu dzykfxrane (jmeqxcnudd )
-
01 Oct 2016
dnpjrpyvfj(mcwtlxqmkj) = sskyjdfnzp dzykfxrane (jmeqxcnudd )
Phase 3
-
-
rsawwjppbu(ttgkfomutt) = Beraprost-314d relaxed constricted PAs with a 4-fold greater potency than beraprost rcmkcieoxb (rqixzakvtm )
-
01 Sep 2015
Phase 2/3
-
dfrgxdgvus(gbjjebzffc) = vygupohukm bvtczttzbr (ioldusqclr )
Positive
05 Nov 2013
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Approval

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Regulation

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